WormBase Tree Display for Strain: WBStrain00006437
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| WBStrain00006437 | Status | Live | ||
|---|---|---|---|---|
| Genotype | sec-5(pk2357)/mIn1 [dpy-10(e128) mIs14] II. | |||
| Public_name | DV2689 | |||
| Contains | Gene | WBGene00001072 | ||
| WBGene00004752 | ||||
| Variation | WBVar00142982 | |||
| WBVar02148856 | ||||
| Rearrangement | mIn1 | |||
| Transgene | WBTransgene00000999 | |||
| Properties | CGC_received | 16 Apr 2012 00:00:00 | ||
| Location | CGC | |||
| Made_by | WBPerson516 | |||
| Remark | Heterozygotes segregate wild-type GFP+ heterozygotes, GFP+ Dpy, and sec-5 homozygotes (scrawny, small broods, abnormal gut appearance) sec-5 is homozygous maternal-effect lethal; M+Z- animals produce a few dead L1-L2 stage larvae with Vab defects. Pick GFP+ wild-type to maintain. Based upon phenotype, pk2357 is a strong loss-of-function, but likely not a null allele; molecular lesion produces a premature stop at position 389. Reference: Frische EW, et al. EMBO J. 2007 Dec 12;26(24):5083-92. [NOTE: This strain was previously described as carrying pk2358, but pk2357 is the correct allele. Both pk2357 and pk2358 cause the same nonsense (amber) change.] | Inferred_automatically | From CGC strain data | |
| Species | Caenorhabditis elegans |
