WormBase Tree Display for Picture: WBPicture0000009749
expand all nodes | collapse all nodes | view schema
| WBPicture0000009749 | Description | (D) High magnification of ventral cord neuronal nuclei reveals that the rescuing UNC-75::GFP protein localizes to subnuclear puncta (green channel, top). UNC-75::GFP puncta do not colocalize with DAPI-stained DNA (lower two panels). (E) Deletion of the predicted nuclear localization signal (Figure 2) leads to loss of UNC-75::GFP subnuclear localization and a diffuse redistribution throughout the nucleo- and cytoplasm, including axons. (F) Subnuclear UNC-75::GFP puncta are dynamic. Images of immobilized animals taken at 10-s intervals in the same focal plane show that UNC-75 speckles are continuously moving/remodeling with the nucleus. See the Supplemental Data for the corresponding movie.(G) Human CELF4/BrunoL4::GFP localizes to subnuclear speckles in transgenic worms. | |||
|---|---|---|---|---|---|
| Name | F3_B.jpg | ||||
| Crop | Cropped_from | WBPicture0000009747 | |||
| Depict | Expr_pattern | Expr2669 | |||
| Cellular_component | GO:0005634 | ||||
| Acknowledgment | Template | Reprinted from <Journal_URL>, <Article_URL>, Copyright <Publication_year>, with permission from <Publisher_URL>. | |||
| Publication_year | 2003 | ||||
| Article_URL | DOI | id | 10.1016/S0960-9822(03)00532-3 | ||
| Journal_URL | CurrentBiology | ||||
| Publisher_URL | Elsevier | ||||
| Reference | WBPaper00006029 |
