WormBase Tree Display for Interaction: WBInteraction000557554
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| WBInteraction000557554 | Interaction_type | Regulatory | Change_of_localization | ||
|---|---|---|---|---|---|
| Interactor | Interactor_overlapping_gene | WBGene00006932 | Interactor_type | Trans_regulator | |
| WBGene00011696 | Interactor_type | Trans_regulated | |||
| Variation_interactor | WBVar00146611 | Interactor_type | Trans_regulator | ||
| Interaction_summary | "We have transformed C. elegans with the heat shock promoter driven gfp:2xT10G3.5(FYVE) fusion construct and analysed its expression pattern. Animals wild type for let-512 showed the strongest expression in the intestinal and hypodermal cells. In these cells, the GFP::2xT10G3.5 (FYVE) fusion protein was targeted to a multitude of intracellular membranes and vesicles, most of them being localized at peripheral regions (Figure 4A and F; data not shown). In arrested let-512(h510) mutant worms the fusion protein was also expressed, but it remained diffusely distributed in the cytosol (Figure 4D). " | ||||
| Detection_method | Reporter_gene | [GFP::T10G3.5] | |||
| Regulation_level | Post_translational | ||||
| Regulation_result | Positive_regulate | Anatomy_term | WBbt:0005772 | ||
| Subcellular_localization | intracellular membranes and vesicles | ||||
| Paper | WBPaper00005216 | ||||
| Remark | Fig. 4 |
