WormBase Tree Display for Gene: WBGene00011696
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| WBGene00011696 | SMap | S_parent | Sequence | T10G3 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | eea-1 | Person_evidence | WBPerson217 | |||||
| Sequence_name | T10G3.5 | ||||||||
| Molecular_name | T10G3.5a | ||||||||
| T10G3.5a.1 | |||||||||
| CE31066 | |||||||||
| T10G3.5b | |||||||||
| CE37989 | |||||||||
| T10G3.5b.1 | |||||||||
| Other_name | CELE_T10G3.5 | Accession_evidence | NDB | BX284605 | |||||
| Public_name | eea-1 | ||||||||
| DB_info | Database | AceView | gene | 5N972 | |||||
| WormQTL | gene | WBGene00011696 | |||||||
| WormFlux | gene | WBGene00011696 | |||||||
| NDB | locus_tag | CELE_T10G3.5 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00011696|UniProtKB=G5ED80 | |||||||
| family | PTHR23164 | ||||||||
| NCBI | gene | 179832 | |||||||
| RefSeq | protein | NM_001028957.5 | |||||||
| NM_001028956.4 | |||||||||
| TREEFAM | TREEFAM_ID | TF329698 | |||||||
| TrEMBL | UniProtAcc | Q5FC45 | |||||||
| G5ED80 | |||||||||
| UniProt_GCRP | UniProtAcc | G5ED80 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:52 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 04 Nov 2004 16:11:20 | WBPerson2970 | Name_change | CGC_name | eea-1 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | eea | ||||||||
| Allele (100) | |||||||||
| Strain | WBStrain00031782 | ||||||||
| WBStrain00036163 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00013516 | ||||||||
| 00013517 | |||||||||
| 00013518 | |||||||||
| 00013519 | |||||||||
| 00013520 | |||||||||
| 00013521 | |||||||||
| 00013522 | |||||||||
| 00013523 | |||||||||
| 00013524 | |||||||||
| 00118935 | |||||||||
| Ortholog (34) | |||||||||
| Paralog | WBGene00007124 | Caenorhabditis elegans | From_analysis | modENCODE_Pseudogenes | |||||
| Structured_description | Concise_description | eea-1 encodes a coiled-coil protein that is the C. elegans ortholog of early endosome antigen 1 (EEA1); eea-1 activity is required for wild-type levels of endocytosis; a fusion protein between EEA-1 FYVE domains and GFP binds endosomal/vacuolar membranes in wild-type worms but not in those lacking vps-34 activity, suggesting that, like its human ortholog, C. elegans EEA-1 binds phosphatidylinositol 3-phosphate (PtdIns 3-P) in vivo; EEA-1 reporter fusion proteins localize to early endosomes. | Paper_evidence | WBPaper00005216 | |||||
| WBPaper00025238 | |||||||||
| WBPaper00028279 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 07 Jan 2011 00:00:00 | ||||||||
| Automated_description | Enables phosphatidylinositol-3-phosphate binding activity. Involved in endocytosis. Located in early endosome and endocytic vesicle. Expressed in hypodermis and intestine. Is an ortholog of human EEA1 (early endosome antigen 1). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | T10G3.5a | |||||||
| T10G3.5b | |||||||||
| Corresponding_CDS_history | T10G3.5:wp80 | ||||||||
| T10G3.5:wp138 | |||||||||
| Corresponding_transcript | T10G3.5a.1 | ||||||||
| T10G3.5b.1 | |||||||||
| Other_sequence (22) | |||||||||
| Associated_feature | WBsf653313 | ||||||||
| WBsf653314 | |||||||||
| WBsf669597 | |||||||||
| WBsf234817 | |||||||||
| Transcription_factor | WBTranscriptionFactor000915 | ||||||||
| Experimental_info | RNAi_result | WBRNAi00078222 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00018557 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00053068 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr11893 | ||||||||
| Expr1023427 | |||||||||
| Expr1035145 | |||||||||
| Expr1156676 | |||||||||
| Expr2011176 | |||||||||
| Expr2029412 | |||||||||
| Drives_construct | WBCnstr00001792 | ||||||||
| Construct_product | WBCnstr00001792 | ||||||||
| WBCnstr00001798 | |||||||||
| WBCnstr00009012 | |||||||||
| Antibody | WBAntibody00000923 | ||||||||
| WBAntibody00001088 | |||||||||
| WBAntibody00001323 | |||||||||
| WBAntibody00001956 | |||||||||
| Microarray_results (25) | |||||||||
| Expression_cluster (122) | |||||||||
| Interaction (35) | |||||||||
| Map_info | Map | V | Position | 5.35055 | Error | 0.000717 | |||
| Positive | Positive_clone | T10G3 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference (21) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
