WormBase Tree Display for Interaction: WBInteraction000557494
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WBInteraction000557494 | Interaction_type | Regulatory | Change_of_localization | ||
---|---|---|---|---|---|
Interactor | Interactor_overlapping_gene | WBGene00003917 | Interactor_type | Trans_regulated | |
Antibody | WBAntibody00001846 | ||||
WBGene00003133 | Interactor_type | Trans_regulator | |||
Variation_interactor | WBVar00094716 | Interactor_type | Trans_regulator | ||
Interaction_summary | "in embryos mutant for the Pod alleles of the APC, PAR-3 is uniformly distributed around the cortex and PAR-2 is present only as cytoplasmic foci (Figures 5A and 5B). In contrast, in embryos mutant for par-3 alone, PAR-2 is still found at the cortex, albeit uniformly (Figure 5C; Etemad-Moghadam et al., 1995)... After depleting PAR-3 in Pod-APC mutant embryos, PAR-2 returns to the cortex in a uniform, nonpolarized distribution (Figures 5D and 5E)." | ||||
Detection_method | Antibody | ||||
Regulation_level | Post_translational | ||||
Regulation_result | Positive_regulate | Life_stage | WBls:0000006 | ||
Subcellular_localization | posterior cortex | ||||
Paper | WBPaper00005095 |