WormBase Tree Display for Gene: WBGene00003917
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| WBGene00003917 | SMap | S_parent | Sequence | F58B6 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | par-2 | Person_evidence | WBPerson314 | |||||
| Sequence_name | F58B6.3 | ||||||||
| Molecular_name (19) | |||||||||
| Other_name | CELE_F58B6.3 | Accession_evidence | NDB | BX284603 | |||||
| Public_name | par-2 | ||||||||
| DB_info | Database | AceView | gene | 3C183 | |||||
| WormQTL | gene | WBGene00003917 | |||||||
| WormFlux | gene | WBGene00003917 | |||||||
| NDB | locus_tag | CELE_F58B6.3 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00003917|UniProtKB=Q965F9 | |||||||
| family | PTHR44080 | ||||||||
| NCBI | gene | 175275 | |||||||
| RefSeq | protein | NM_001420607.1 | |||||||
| NM_001027459.7 | |||||||||
| NM_001420609.1 | |||||||||
| NM_001420606.1 | |||||||||
| NM_001381725.1 | |||||||||
| TrEMBL | UniProtAcc | A0A8S4SQT8 | |||||||
| A0A8S4SL65 | |||||||||
| A0A8S4SK97 | |||||||||
| H1ZUX3 | |||||||||
| Q965F9 | |||||||||
| UniProt_GCRP | UniProtAcc | A0A8S4SQT8 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:33 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 02 Jan 2022 21:17:43 | WBPerson1983 | Event | Split_into | WBGene00306125 | ||||
| Split_into | WBGene00306125 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | par | ||||||||
| Allele (329) | |||||||||
| Legacy_information | it46ts mat : homozygous hermaphrodites produce 90% (16x) to 99% (25x) arrested embryos escapers sterile; abnormal early cleavages defective P granule localization. ES3 (progeny). NA4 (it5ts : weaker phenotype e2030 : grandchildless). | ||||||||
| See also e2030 | |||||||||
| [C.elegansII] it46ts,mat : homozygous hermaphrodites produce 90% (16C) to 99% (25C) arrested embryos, escapers sterile; abnormal early cleavages, both spindles transverse at 2nd cleavage (failure of P1 rotation), defective P granule localization. ES3 (progeny). OA7: it5ts (weaker phenotype), e2030 (Mes, grandchildless),it87 (weak),jb2, etc. All ts; temp shift indicates not needed after 2nd cleavage. Cloned: encodes predicted novel protein. Antibody staining indicates specific asymmetric cortical localizations in early blastomeres. [Cheng et al. 1995; KK] | |||||||||
| Strain (17) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (26) | |||||||||
| Contained_in_operon | CEOP3056 | ||||||||
| Ortholog (22) | |||||||||
| Structured_description | Concise_description | par-2 encodes a protein containing a C3HC4-type RING-finger, a specialized type of zinc-finger found in E3 ubiquitin ligase subunits; PAR-2 is required maternally for polarization of the C. elegans zygote along the anterior-posterior (A-P) axis and is asymmetrically localized to the posterior cortex of the one- and two-cell embryo via interdependent interactions with PAR-3, PAR-6, and PKC-3. | Paper_evidence | WBPaper00005115 | |||||
| WBPaper00005317 | |||||||||
| WBPaper00005405 | |||||||||
| WBPaper00005575 | |||||||||
| WBPaper00005735 | |||||||||
| WBPaper00005778 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Enables microtubule binding activity; phosphatidylinositol phosphate binding activity; and protein kinase binding activity. Involved in asymmetric cell division; asymmetric protein localization involved in cell fate determination; and establishment of mitotic spindle orientation. Located in P granule; posterior cell cortex; and protein-containing complex. Expressed in germ line. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | F58B6.3a | |||||||
| F58B6.3b | |||||||||
| F58B6.3c | |||||||||
| F58B6.3d | |||||||||
| F58B6.3e | |||||||||
| Corresponding_CDS_history | F58B6.3:wp19 | ||||||||
| F58B6.3a:wp229 | |||||||||
| F58B6.3a:wp283 | |||||||||
| F58B6.3b:wp150 | |||||||||
| Corresponding_transcript | F58B6.3a.1 | ||||||||
| F58B6.3b.1 | |||||||||
| F58B6.3c.1 | |||||||||
| F58B6.3d.1 | |||||||||
| F58B6.3e.1 | |||||||||
| F58B6.3e.2 | |||||||||
| F58B6.3e.3 | |||||||||
| F58B6.3e.4 | |||||||||
| F58B6.3e.5 | |||||||||
| Other_sequence | CR05646 | ||||||||
| CRC02017_1 | |||||||||
| MPC00003_1 | |||||||||
| Associated_feature (14) | |||||||||
| Experimental_info | RNAi_result (96) | ||||||||
| Expr_pattern (11) | |||||||||
| Drives_construct | WBCnstr00009161 | ||||||||
| WBCnstr00009162 | |||||||||
| WBCnstr00009163 | |||||||||
| WBCnstr00009164 | |||||||||
| WBCnstr00009165 | |||||||||
| WBCnstr00009166 | |||||||||
| WBCnstr00009167 | |||||||||
| WBCnstr00009168 | |||||||||
| WBCnstr00009170 | |||||||||
| Construct_product (13) | |||||||||
| Antibody (11) | |||||||||
| Microarray_results (23) | |||||||||
| Expression_cluster (108) | |||||||||
| Interaction (370) | |||||||||
| WBProcess | WBbiopr:00000017 | ||||||||
| Map_info | Map | III | Position | -23.7021 | Error | 0.225136 | |||
| Well_ordered | |||||||||
| Positive | Positive_clone | F58B6 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Y11F11 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||||
| Mapping_data | 2_point | 2720 | |||||||
| 2721 | |||||||||
| 4699 | |||||||||
| Multi_point (11) | |||||||||
| Landmark_gene | |||||||||
| Reference (312) | |||||||||
| Method | Gene |
