WormBase Tree Display for Interaction: WBInteraction000550465
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| WBInteraction000550465 | Interaction_type | Regulatory | Change_of_expression_level | ||
|---|---|---|---|---|---|
| Interactor | Interactor_overlapping_gene | WBGene00000935 | Interactor_type | Trans_regulator | |
| WBGene00003043 | Interactor_type | Trans_regulated | |||
| Interaction_summary | "all solid granule modulators were depleted in a set of 21 transgenic strains that express gfp::his-11 reporter mRNAs regulated by different 3' UTRs (Fig. 7; Merritt et al., 2008)... RNAi of 22/66 solid modulators strongly increased GFP levels from one or more reporters (17) or weakly increased GFP from at least two reporters (5), revealing genes that repress expression (Figs. 7 B and S2). Depletion of 20 genes decreased GFP from various reporters indicating factors that activate or support expression (Fig. S2). Some repressive genes fell into both classes; RNAi de-repressed some reporters but reduced expression of others (Figs. 7 B and S2)." | ||||
| Detection_method | Reporter_gene | [lip-1p::gfp] | |||
| Regulation_result | Positive_regulate | Life_stage | WBls:0000041 | ||
| Anatomy_term | WBbt:0005784 | ||||
| Paper | WBPaper00048752 | ||||
| Remark | Fig. 7B |
