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WormBase Tree Display for Interaction: WBInteraction000549840

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Name Class

WBInteraction000549840Interaction_typeRegulatoryChange_of_expression_level
InteractorInteractor_overlapping_geneWBGene00003999Interactor_typeTrans_regulated
TransgeneWBTransgene00000017
ConstructWBCnstr00000017
WBGene00004055Interactor_typeTrans_regulator
Interaction_summary"To identify the signalling components that are required for induction of pgp-5::gfp or gst-4::gfp in the intestine in response to the iff-1(tm483) or rpl-11.1(ar228) germline-translation-defective mutations, we screened a 450-gene kinase and 600-gene transcription factor RNAi library (Methods and Supplementary Tables 4 and 5). Positive hits from the screen were rescreened on the eft-3(q145);pgp-5::gfp germline-translation-defective strain, and most were required for pgp-5::gfp induction in eft-3(q145) (Fig. 3a,b)."
Detection_methodConstruct
Reporter_gene[pgp-5::gfp]
Transgene
Regulation_resultNegative_regulateLife_stageWBls:0000041
PaperWBPaper00048491
RemarkTable S5