WormBase Tree Display for Interaction: WBInteraction000542948
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| WBInteraction000542948 | Interaction_type | Regulatory | Change_of_expression_level | ||
|---|---|---|---|---|---|
| Interactor | Interactor_overlapping_gene | WBGene00004202 | Interactor_type | Trans_regulator | |
| WBGene00018573 | Interactor_type | Trans_regulated | |||
| WBGene00012046 | Interactor_type | Trans_regulated | |||
| WBGene00022104 | Interactor_type | Trans_regulated | |||
| Variation_interactor | WBVar00089203 | Interactor_type | Trans_regulator | ||
| Interaction_summary | "qPCR analysis showed that fifteen of the eighteen genes analyzed showed decreased expression in the bar-1(ga80) background, and 11 of 18 BAR-1 responsive genes showed increased expression in a pry-1(mu38) background (Table 1). Four genes (E03H4.4, srw-93, fbxa-116, dod-23) did not display the behavior predicted for a Wnt target gene in these backgrounds." | ||||
| Detection_method | RT_PCR | ||||
| Regulation_level | Transcriptional | ||||
| Paper | WBPaper00044857 | ||||
| Remark | Table 1; "To conditionally activate Wnt signaling, we used hs::DNTbar-1, a transgene that uses the heat shock promoter to express a BAR-1 protein with an amino-terminal deletion (DNTBAR-1) predicted to stabilize the protein in the absence of Wnt signaling (Figure 1A) (Gleason et al. 2002)." |
