WormBase Tree Display for Interaction: WBInteraction000541261
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| WBInteraction000541261 | Interaction_type | Regulatory | Change_of_expression_level | ||
|---|---|---|---|---|---|
| Interactor | Interactor_overlapping_gene | WBGene00015547 | Interactor_type | Trans_regulator | |
| WBGene00015007 | Interactor_type | Trans_regulator | |||
| WBGene00001824 | Interactor_type | Trans_regulated | |||
| WBGene00009394 | Interactor_type | Trans_regulated | |||
| WBGene00017964 | Interactor_type | Trans_regulated | |||
| WBGene00019564 | Interactor_type | Trans_regulated | |||
| WBGene00016788 | Interactor_type | Trans_regulated | |||
| WBGene00020760 | Interactor_type | Trans_regulated | |||
| WBGene00003561 | Interactor_type | Trans_regulated | |||
| WBGene00006627 | Interactor_type | Trans_regulated | |||
| Variation_interactor | WBVar00250826 | Interactor_type | Trans_regulator | ||
| WBVar00088360 | Interactor_type | Trans_regulator | |||
| Interaction_summary | "we examined mRNA levels of a subset of these genes in ain-2[reduction-of-function (rf)];ain-1(lf) double mutants in which miRISC activity is strongly and specifically reduced (Zhang et al., 2007). We found a significant upregulation in eight of the nine AIN-2-associated, dcr-1- and pathogen-responsive genes we tested (we refer to these genes as miRISC-regulated pathogen-response [MRPR] genes hereafter) (Figure 4B). As controls, we examined the expression of ges-1 (an intestine-specific, pathogen nonresponsive gene), F08G5.6 (a pathogen-responsive gene encoding mRNAs that were not detected in the miRISC), and sod-3 (a general stressinduced gene) and found no change in the expression of these genes in ain-2(rf);ain-1(lf) double mutants." | ||||
| Detection_method | RT_PCR | ||||
| Regulation_result | Negative_regulate | Anatomy_term | WBbt:0005792 | ||
| Paper | WBPaper00040985 | ||||
| Remark | Fig. 4b |
