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WormBase Tree Display for Interaction: WBInteraction000521915

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Name Class

WBInteraction000521915Interaction_typeGeneticEnhancement
GI_module_twoEnhancing
InteractorInteractor_overlapping_geneWBGene00011195Interactor_typeEffector
WBGene00001609Interactor_typeAffected
Variation_interactorWBVar00094366Interactor_typeEffector
WBVar00000230Interactor_typeAffected
Interaction_summaryAt the permissive temperature of 20 deg C, where virtually all glp-1 (ar202) animals are fertile, 15% of glp-1(ar202); sao-1 (ok3335) double mutants are completely sterile, and even the fertile animals appear to have aberrant germ lines; fertile glp-1(ar202); sao-1(ok3335) double mutants have small brood sizes averaging only 50.6 progeny ( 25.7 SD; n = 31) compared to an average of 151 progeny ( 63.6 SD; n = 20) for single glp-1(ar202) animals; The percentage of gonad arms that display tumorous germline (Tum) or proximal mitosis(Pro) at 20 deg C is significantly greater for the glp-1(ar202); sao-1(ok3335) double mutants (37%, n = 452 gonad arms) than for the glp-1(ar202) single mutants
ThroughputLow_throughput
Interaction_phenotypeWBPhenotype:0000688
WBPhenotype:0000812
WBPhenotype:0001033
WBPhenotype:0001038
WBProcessWBbiopr:00000032
PaperWBPaper00040544