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WormBase Tree Display for Interaction: WBInteraction000521439

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Name Class

WBInteraction000521439Interaction_typeGeneticSuppression
GI_module_twoSuppressing
InteractorInteractor_overlapping_geneWBGene00003847Interactor_typeEffector
WBGene00001089Interactor_typeAffected
Variation_interactorWBVar00249587Interactor_typeEffector
WBVar00142822Interactor_typeAffected
Interaction_summaryIn dre-1 partial loss-of-function mutants (e.g., dre- 1(dh99)) seam cells undergo precocious terminal differentiation in L3, a full stage ahead of schedule. Using the adherens junction marker ajm-1:gfp to mark seam cell boundaries, we observed that blmp-1 knockdown by RNAi reduced dre-1(dh99) precocious seam cell fusion from 90% to 15% of the animals. Similarly only 7.5% of dre-1;blmp-1(tm548) double mutant animals showed seam cell fusion in L3.
ThroughputLow_throughput
Interaction_phenotypeWBPhenotype:0000033
WBPhenotype:0001433
WBPhenotype:0000167
WBProcessWBbiopr:00000083
PaperWBPaper00045017