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WormBase Tree Display for Interaction: WBInteraction000501673

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Name Class

WBInteraction000501673Interaction_typeRegulatoryChange_of_expression_level
InteractorInteractor_overlapping_geneWBGene00001484Interactor_typeTrans_regulator
WBGene00006962Interactor_typeTrans_regulated
Interaction_summaryThe level of FOX-1 produced by yIs44 causes complete XO-specific lethality in otherwise wild-type strains. In yIs44 strains with the gfp::xol-1 arrays, no GFP expression was detected and all the XO animals died. These results indicate that high doses of FOX-1 drastically reduce the levels of both the GFP::XOL-1 protein and the endogenous XOL-1 protein, revealing that FOX-1 acts through xol-1.
Detection_methodReporter_gene[xol-1::gfp]
Regulation_levelPost_transcriptional
PaperWBPaper00002827