WormBase Tree Display for Interaction: WBInteraction000003228
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| WBInteraction000003228 | Interaction_type | Regulatory | Change_of_expression_level | ||
|---|---|---|---|---|---|
| Interactor | Interactor_overlapping_gene | WBGene00006926 | Interactor_type | Trans_regulated | |
| Expr_pattern | Expr12138 | ||||
| Construct | WBCnstr00020271 | ||||
| WBGene00003100 | Interactor_type | Trans_regulator | |||
| Variation_interactor | WBVar00143854 | Interactor_type | Trans_regulator | ||
| Interaction_summary | The vit-2::GFP reporter is expressed in wild-type hermaphrodites, but not in wild-type males. In contrast, mab-3 mutants express the vit-2::GFP reporter at high levels in both sexes. Eliminating mab-3 activity abolishes the sex-specificity of vit promoter activity, but stage-specificity and tissue-specificity are unaffected. The misexpression of vit-2::GFP in mab-3 mutant males suggests that mab-3 regulates vitellogenin transcription. | ||||
| Detection_method | Construct | ||||
| Regulation_level | Transcriptional | ||||
| Regulation_result | Negative_regulate | Life_stage | WBls:0000056 | ||
| Anatomy_term | WBbt:0005772 | ||||
| Paper | WBPaper00003452 |
