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WormBase Tree Display for Gene: WBGene00302980

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Name Class

WBGene00302980SMapS_parentSequenceF53E2
IdentityVersion1
NameSequence_nameF53E2.2
Molecular_nameF53E2.2
F53E2.2.1
CE20547
Other_nameCELE_F53E2.2Accession_evidenceNDBBX284605
Public_nameF53E2.2
DB_infoDatabaseNDBlocus_tagCELE_F53E2.2
NCBIgene41657006
RefSeqproteinNM_071024.9
SwissProtUniProtAccQ07750
UniProt_GCRPUniProtAccQ07750
OMIMgene601443
SpeciesCaenorhabditis elegans
HistoryVersion_change106 Mar 2018 14:39:08WBPerson4025EventSplit_fromWBGene00006794
Split_fromWBGene00006794
StatusLive
Gene_infoBiotypeSO:0001217
Allele (43)
RNASeq_FPKM (74)
GO_annotation (36)
Contained_in_operonCEOP5600
Ortholog (42)
ParalogWBGene00006794Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionAutomated_descriptionEnables actin filament binding activity. Involved in several processes, including actin filament-based process; embryo development; and positive regulation of actin filament polymerization. Located in striated muscle thin filament. Part of ribonucleoprotein complex. Human ortholog(s) of this gene implicated in brain compression; gallbladder carcinoma; and nemaline myopathy 7. Is an ortholog of human CFL2 (cofilin 2).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:4948Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:1874)
DOID:0110934Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:1875)
DOID:11457Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:1874)
Molecular_infoCorresponding_CDSF53E2.2
Corresponding_transcriptF53E2.2.1
Experimental_infoRNAi_result (39)
Microarray_results (30)
Expression_cluster (55)
InteractionWBInteraction000519090
WBInteraction000581343
Map_infoMapV
PositivePositive_cloneF53E2Inferred_automaticallyFrom sequence, transcript, pseudogene data
Interpolated_map_positionV-18.8782
MethodGene