WormBase Tree Display for Gene: WBGene00302980

WBGene00302980 SMap: S_parent: Sequence: F53E2
  Identity: Version: 1
    Name: Sequence_name: F53E2.2
      Molecular_name: F53E2.2
        F53E2.2.1
        CE20547
      Other_name: CELE_F53E2.2 Accession_evidence: NDB BX284605
      Public_name: F53E2.2
    DB_info: Database: NDB locus_tag CELE_F53E2.2
        NCBI gene 41657006
        RefSeq protein NM_071024.9
        SwissProt UniProtAcc Q07750
        UniProt_GCRP UniProtAcc Q07750
        OMIM gene 601443
    Species: Caenorhabditis elegans
    History: Version_change: 1 06 Mar 2018 14:39:08 WBPerson4025 Event: Split_from: WBGene00006794
      Split_from: WBGene00006794
    Status: Live
  Gene_info: Biotype: SO:0001217
    Allele (43)
    RNASeq_FPKM (74)
    GO_annotation (36)
    Contained_in_operon: CEOP5600
    Ortholog (42)
    Paralog: WBGene00006794 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Automated_description: Enables actin filament binding activity. Involved in several processes, including actin filament-based process; embryo development; and positive regulation of actin filament polymerization. Located in striated muscle thin filament. Part of ribonucleoprotein complex. Human ortholog(s) of this gene implicated in brain compression; gallbladder carcinoma; and nemaline myopathy 7. Is an ortholog of human CFL2 (cofilin 2). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:4948 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1874)
      DOID:0110934 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1875)
      DOID:11457 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1874)
  Molecular_info: Corresponding_CDS: F53E2.2
    Corresponding_transcript: F53E2.2.1
  Experimental_info: RNAi_result (39)
    Microarray_results (30)
    Expression_cluster: WBPaper00054189:aging_regulated_protein
      WBPaper00054189:P.aeruginosa_regulated_protein
      WBPaper00060951:mrpl-2(osa3)_upregulated
      WBPaper00061439:unc-30(ok613)_upregulated
      WBPaper00061651:Distal_tip_cell_enriched
      WBPaper00061651:Spermatheca_enriched
      WBPaper00062002:Day4-adult_secretome
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00064071:NHR-49_interacting
      WBPaper00064163:ZNFX-1_interacting_embryo
      WBPaper00064992:Capsaicin_downregulated
      WBPaper00064992:Eugenol_downregulated
      cgc4386_cluster_3_5
      cgc4386_cluster_5_4
      cgc4386_cluster_6_3
      WBPaper00025032:cluster_62
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00031003:0hr_muscle_depleted
      WBPaper00031003:24hr_muscle_depleted
      WBPaper00031003:total_muscle_depleted
      WBPaper00031832:slr-2_regulated
      WBPaper00034739:N2moreDR1350
      WBPaper00035588:alg-1(-)_upregulated
      WBPaper00035905:FBF-1_Associated
      WBPaper00037695:WC_5-day
      WBPaper00037901:GLD-1_mRNA_targets
      WBPaper00038231:Cry5B_1.5-fold_upregulated
      WBPaper00038231:Cry5B_2-fold_upregulated
      WBPaper00039866:ClassComp_daf-19_upregulated
      WBPaper00040184:hcf-1nc_sir-2.1nc_daf-2down
      WBPaper00040184:hcf-1nc_sir-2.1nc_daf-2up
      WBPaper00040963:TA200_down
      WBPaper00040963:TA300_down
      WBPaper00041606:CE_B.thuringiensis-DB27_regulated
      WBPaper00041606:CE_S.marcescens_regulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_24h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_51h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_24h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h
      WBPaper00044535:male_upregulated
      WBPaper00047070:N2_starvation_downregulated
      WBPaper00053550:daf-19(m86)_upregulated_3-fold-embryo
      WBPaper00057098:SiO2-nanoparticles_upregulated
      [cgc5767]:expression_class_E
      [cgc5767]:expression_class_E_pi(101_min)
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_ME
      [cgc5767]:expression_class_SM
    Interaction: WBInteraction000519090
      WBInteraction000581343
  Map_info: Map: V
    Positive: Positive_clone: F53E2 Inferred_automatically: From sequence, transcript, pseudogene data
    Interpolated_map_position: V -18.8782
  Method: Gene