| WBGene00050875 | SMap | S_parent | Sequence | ZK1025 |
|---|
| Identity | Version | 2 |
| | Name | CGC_name | bah-1 | Paper_evidence | WBPaper00035152 |
| | | | | Person_evidence | WBPerson125 |
| | | Sequence_name | ZK1025.7 |
| | | Molecular_name | ZK1025.7 |
| | | | ZK1025.7.1 |
| | | | CE19334 |
| | | Other_name | CELE_ZK1025.7 | Accession_evidence | NDB | BX284601 |
| | | Public_name | bah-1 |
| | DB_info | Database (12) |
| | Species | Caenorhabditis elegans |
| | History | Version_change | 1 | 31 Jul 2007 09:27:58 | WBPerson2970 | Event | Created |
| | | | 2 | 07 Sep 2009 16:20:54 | WBPerson1847 | Event | Acquires_merge | WBGene00014187 |
| | | Acquires_merge | WBGene00014187 |
| | Status | Live |
| Gene_info | Biotype | SO:0001217 |
| | Gene_class | bah |
| | Allele (64) |
| | Strain | WBStrain00032417 |
| | | WBStrain00004729 |
| | | WBStrain00004755 |
| | | WBStrain00005601 |
| | RNASeq_FPKM (74) |
| | GO_annotation | 00104538 |
| | | 00104539 |
| | | 00104540 |
| | | 00104541 |
| | Ortholog (45) |
| | Paralog (38) |
| | Structured_description | Concise_description | bah-1 encodes a protein with a DUF23 domain, a domain found in insects, plants, bacteria and two vertebrates, the frog and the fish, Tetraodon, but absent from mammalian genomes; bah-1 normally functions to contribute to the integrity of the nematode cuticle; bah-1 is also required for the surface characteristics of the elegans cuticle that are required for the binding of bacterial biofilms; bah-1 expression is down-regulated in mutants of the TGF-beta pathway, like daf-7, daf-8 or daf-14, as such, these mutants do not form biofilms, suggesting that the TGF-beta pathway regulates bah-1 and possibly other genes required for biofilm binding; bah-1 is expressed in the seam cells which are part of the cuticle-synthesizing hypodermis. | Paper_evidence | WBPaper00035152 |
| | | | | Curator_confirmed | WBPerson324 |
| | | | | Date_last_updated | 19 Sep 2011 00:00:00 |
| | | Automated_description | Predicted to enable glycosyltransferase activity. Predicted to be located in membrane. Expressed in seam cell. Used to study bacterial infectious disease. | Paper_evidence | WBPaper00065943 |
| | | | | Curator_confirmed | WBPerson324 |
| | | | | | WBPerson37462 |
| | | | | Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase |
| | | | | Date_last_updated | 29 Nov 2023 00:00:00 |
| Disease_info | Experimental_model | DOID:104 | Homo sapiens | Paper_evidence | WBPaper00035152 |
| | | | | Curator_confirmed | WBPerson324 |
| | | | | Date_last_updated | 13 Mar 2023 00:00:00 |
| | Disease_relevance | C. elegans is being used as a model system to identify and study the genes required for the formation of bacterial biofilms in the host; the inherent resistance of biofilms to antimicrobial agents like phagocytes, antibiotics etc, are the root cause of chronic bacterial infections; the bah genes in elegans, bah-1, bah-2 and bah-3 are required for infection of elegans by biofilm producing bacteria Yersinia pestis and Yersinia pseudotuberculosis, which bind to the C. elegans surface, predominantly on the head. | Homo sapiens | Paper_evidence | WBPaper00006215 |
| | | | | | WBPaper00035152 |
| | | | | Curator_confirmed | WBPerson324 |
| | | | | Date_last_updated | 19 Sep 2011 00:00:00 |
| Models_disease_in_annotation | WBDOannot00000010 |
| Molecular_info | Corresponding_CDS | ZK1025.7 |
| | Corresponding_transcript | ZK1025.7.1 |
| | Other_sequence | CR08419 |
| | | CRC03784_1 |
| | Associated_feature | WBsf218537 |
| | | WBsf218538 |
| Experimental_info | RNAi_result | WBRNAi00059046 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00082255 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00059047 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00004903 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00004905 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00082265 | Inferred_automatically | RNAi_primary |
| | Expr_pattern | Expr12811 |
| | | Expr1011822 |
| | | Expr1040381 |
| | | Expr1162477 |
| | | Expr2009528 |
| | | Expr2027765 |
| | Drives_construct | WBCnstr00022882 |
| | | WBCnstr00022883 |
| | | WBCnstr00023201 |
| | Construct_product | WBCnstr00022882 |
| | | WBCnstr00022883 |
| | | WBCnstr00023201 |
| | Microarray_results (13) |
| | Expression_cluster | WBPaper00024505:pharyngeal_enriched |
| | | WBPaper00031040:TGF-beta_adult_upregulated |
| | | WBPaper00036231:long-telomeres_downregulated |
| | | WBPaper00036375:enriched_in_PVD_OLL |
| | | WBPaper00037682:sma-2_sma-4_upregulated |
| | | WBPaper00037950:A-class-motor-neurons_L1-larva_expressed |
| | | WBPaper00037950:AVE-neuron_L1-larva_expressed |
| | | WBPaper00037950:bodywall-muscle_L1-larva_expressed |
| | | WBPaper00037950:hypodermis_L1-larva_expressed |
| | | WBPaper00037950:pharyngeal-muscle_L1-larva_expressed |
| | | WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed |
| | | WBPaper00038168:lin-15B(n744)_downregulated |
| | | WBPaper00038438:D.coniospora_12hr_downregulated_RNAseq |
| | | WBPaper00038438:E.faecalis_24hr_upregulated_RNAseq |
| | | WBPaper00038438:P.lumniescens_24hr_upregulated_RNAseq |
| | | WBPaper00038438:P.lumniescens_24hr_upregulated_TilingArray |
| | | WBPaper00038438:S.marcescens_24hr_upregulated_RNAseq |
| | | WBPaper00041954:ethanol_upregulated |
| | | WBPaper00042194:nhr-114(RNAi)_downregulated |
| | | WBPaper00042194:Tryptophan_downregulated |
| | | WBPaper00042561:smg-2(RNAi)_upregulated |
| | | WBPaper00042561:smgl-1(RNAi)_upregulated |
| | | WBPaper00043945:MeHg_upregulated |
| | | WBPaper00044260:1-methylnicotinamide_upregulated |
| | | WBPaper00044578:reduced-humidity_downregulated_microarray |
| | | WBPaper00044736:oscillating_dev_expression |
| | | WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_upregulated |
| | | WBPaper00045316:prg-1_downregulated_L1 |
| | | WBPaper00045390:ubc-9(RNAi)_upregulated |
| | | WBPaper00045774:clk-1_downregulated |
| | | WBPaper00045934:wrn-1(gk99)_upregulated |
| | | WBPaper00049377:MWCNT_upregulated |
| | | WBPaper00049732:blmp-1(tm548);daf-7(e1372ts)_vs_daf-7(e1372ts)_downregulated |
| | | WBPaper00049920:Glucose-Diet_upregulated_hyl-2(tm2031) |
| | | WBPaper00049942:hsf-1(RNAi)_downregulated |
| | | WBPaper00050743:elli-1(sam-3)_downregulated |
| | | WBPaper00050801:DAF-12_dauer_regulome |
| | | WBPaper00050801:DAF-16_dauer_regulome |
| | | WBPaper00050801:DPY-21_dauer_regulome |
| | | WBPaper00050801:SET-4_dauer_regulome |
| | | WBPaper00050990:hypodermis_enriched |
| | | WBPaper00050990:hypodermis_expressed |
| | | WBPaper00051404:alg-2(ok304)_upregulated |
| | | WBPaper00053020:sid-3(ok973)_upregulated |
| | | WBPaper00053154:human-amyloid-beta_tau_regulated |
| | | WBPaper00053295:lin-22(ot269)_upregulated |
| | | WBPaper00053388:dauer_regulated_Cluster6 |
| | | WBPaper00053402:cco-1(RNAi)_downregulated |
| | | WBPaper00053810:daf-2(e1370)_downregulated |
| | | WBPaper00053810:isp-1(qm150)_downregulated |
| | | WBPaper00053810:nuo-6(qm200)_downregulated |
| | | WBPaper00053888:drh-3(rrr2)_upregulated |
| | | WBPaper00053909:N2_vs_CB4856_upregulated |
| | | WBPaper00054493:hpl-2(tm1489)_upregulated |
| | | WBPaper00055013:hmg-3(bar24)_downregulated |
| | | WBPaper00055013:spt-16(RNAi)_downregulated |
| | | WBPaper00055941:nuo-6(qm200);atfs-1(gk3094)_upregulated |
| | | WBPaper00055941:nuo-6(qm200)_downregulated |
| | | WBPaper00055971:nhl-2(ok818)_25C_downregulated |
| | | WBPaper00056169:rrf-3(pk1426)_downregulated_L3 |
| | | WBPaper00056169:rrf-3(pk1426)_downregulated_L4 |
| | | WBPaper00056284:ints-11(RNAi)_downregulated |
| | | WBPaper00056290:hsp-6(mg585)_upregulated |
| | | WBPaper00056290:mdt-15(mg584)_upregulated |
| | | WBPaper00056471:S.aureus-4h_downregulated_N2 |
| | | WBPaper00057068:ints-4(RNAi)_downregulated |
| | | WBPaper00057068:ints-4(RNAi)_downregulated_Cadmium |
| | | WBPaper00057068:numr-1(RNAi)_downregulated |
| | | WBPaper00057196:raga-1(ok386)_downregulated) |
| | | WBPaper00057347:nhr-14(tm1473)_downreglated |
| | | WBPaper00058598:mex-1(or286)_upregulated |
| | | WBPaper00058598:mex-3(eu149)_upregulated |
| | | WBPaper00058598:sin-3(tm1276)_downregulated |
| | | WBPaper00058927:high-redox-state_upregulated |
| | | WBPaper00058969:RIS_depleted |
| | | WBPaper00059117:B.subtilis_upregulated |
| | | WBPaper00059231:alh-6(lax105)_L4_upregulated |
| | | WBPaper00059253:stearic-acid_downregulated |
| | | WBPaper00059253:sucrose_downregulated |
| | | WBPaper00059253:sucrose_stearic-acid_downregulated |
| | | WBPaper00059328:mrps-5(RNAi)_downregulated_mRNA |
| | | WBPaper00059537:ngn-1(ok2200)_upregulated |
| | | WBPaper00059566:wdr-23(mac32)_upregulated |
| | | WBPaper00059567:olrn-1(ums9)_regulated |
| | | WBPaper00059739:hira-1(gk835598)_downregulated_L1 |
| | | WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi) |
| | | WBPaper00060358:B.thuringiensis_pathogen_regulated_N2 |
| | | WBPaper00060445:ikb-1(nr2027)_downregulated_L4 |
| | | WBPaper00060445:nfki-1(cer1)_downregulated_L4 |
| | | WBPaper00060683:hlh-11(ko1)_upregulated |
| | | WBPaper00060811:L1_vs_adult_downregulated_neural |
| | | WBPaper00060909:atfs-1(et18)_downregulated |
| | | WBPaper00061007:HB101_upregulated |
| | | WBPaper00061007:S.aquatilis_upregulated |
| | | WBPaper00061007:X.citri_upregulated |
| | | WBPaper00061081:skpo-1(ok1640)_upregulated_OP50 |
| | | WBPaper00061203:sin-3(tm1276)_upregulated |
| | | WBPaper00061203:spr-1(ok2144)_upregulated |
| | | WBPaper00061340:Glia |
| | | WBPaper00061340:URA_parent |
| | | WBPaper00061341:28C_48h_upregulated |
| | | WBPaper00061439:unc-30(ok613)_upregulated_P.aeruginosa-infection |
| | | WBPaper00061527:col-128-cdh-10_9234 |
| | | WBPaper00061613:human-alpha-Synuclein(A53T)_upregulated |
| | | WBPaper00061613:human-amyloid-beta_alpha-Synuclein(A53T)_upregulated |
| | | WBPaper00061753:csr-1(tor159)_upregulated_25C |
| | | WBPaper00061952:daf-18(nr2037)_upregulated |
| | | WBPaper00061952:daf-18(yh1)_upregulated |
| | | WBPaper00062156:jmjd-1.2(zr1010)_upregulated |
| | | WBPaper00062156:jmjd-5(zr1234)_upregulated |
| | | WBPaper00062159:hda-2(ok1479)_upregulated |
| | | WBPaper00062446:nhr-8(hd117)_upregulated |
| | | WBPaper00062534:fat-P-80_downregulated |
| | | WBPaper00064088:Day-1-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141) |
| | | WBPaper00064088:Day-1-adult_vs_L4_downregulated_fem-3(q20) |
| | | WBPaper00064088:Day-1-adult_vs_L4_downregulated_glp-1(e2141) |
| | | WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141) |
| | | WBPaper00064088:Day-3-adult_vs_L4_downregulated_fem-3(q20) |
| | | WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141) |
| | | WBPaper00064532:pals-25(icb98)_downregulated |
| | | WBPaper00064539:nhr-114(gk849)_downregulated |
| | | WBPaper00064661:lpd-3(ok2138)_upregulated |
| | | WBPaper00064721:fasn-1(g14)_downregulated_starved |
| | | WBPaper00064728:cpl-1(W32AY35A)_upregulated |
| | | WBPaper00064933:bcf-1(ylf1)_upregulated_transcript |
| | | WBPaper00065029:cadmium_downregulated |
| | | WBPaper00065096:25C_vs_20C_downregulated |
| | | WBPaper00065096:Day10_vs_Day1_downregulated |
| | | WBPaper00065096:npr-8(ok1439)_downregulated_Day10_20C |
| | | WBPaper00065288:mdt-15(tm2182)_downregulated |
| | | WBPaper00065581:hpk-1(pk1393)_upregulated |
| | | WBPaper00065746:eat-2(ad1113)_downregulated |
| | | WBPaper00065877:rege-1(imm070)_downregulated_PA14 |
| | | WBPaper00066110:Cisplatin_upregulated_diploid |
| | | WBPaper00066110:Doxorubicin_upregulated_diploid |
| | | WBPaper00066110:tetraploid_vs_diploid_upregulated |
| | | WBPaper00066204:CdCl2_upregulated_mRNA |
| | | WBPaper00066232:ash-2(RNAi)_downregulated_WT |
| | | cgc4386_cluster_4_6 |
| | | cgc4489_group_8 |
| | | WBPaper00024393:strongly_regulated_dauer_genes |
| | | WBPaper00026929:Resveratrol_regulated_daf-16 |
| | | WBPaper00026952:class_E |
| | | WBPaper00034739:N2lessDR1350 |
| | | WBPaper00035873:dpy-9_regulated |
| | | WBPaper00035873:dpy-10_regulated |
| | | WBPaper00036286:Pattern_G |
| | | WBPaper00036383:ash-2_L3_regulated |
| | | WBPaper00038172:aak-2overexpression_up_regulated |
| | | WBPaper00038172:tax-6null_up_regulated |
| | | WBPaper00038304:octr-1_regulated |
| | | WBPaper00040116:pRJ-FR.5_down_regulated |
| | | WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2 |
| | | WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.5 |
| | | WBPaper00040858:eQTL_age_regulated_developing |
| | | WBPaper00040858:eQTL_regulated_developing |
| | | WBPaper00040858:eQTL_regulated_juvenile |
| | | WBPaper00040876:mir-35_upregulated |
| | | WBPaper00041207:CE_dauer_down |
| | | WBPaper00041939:control_vs_UVC-EtBr-exposed_48h |
| | | WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h |
| | | WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h |
| | | WBPaper00042128:gei-8(ok1671)_downregulated |
| | | WBPaper00042274:tbx-2(bx59)_upregulated |
| | | WBPaper00046083:oga-1(ok1207)_OP50_downregulated |
| | | WBPaper00046083:ogt-1(ok1474)_OP50_downregulated |
| | | WBPaper00046083:pmk-1(km25)_OP50_downregulated |
| | | WBPaper00046548:dafachronic-acid_upregulated |
| | | WBPaper00046853:AOBr_M.aeruginosa-batch-culture_downregulated |
| | | WBPaper00047070:N2_starvation_downregulated |
| | | WBPaper00047070:N2_UV_downregulated |
| | | WBPaper00047070:xpa-1_UV_downregulated |
| | | WBPaper00057098:SiO2-nanoparticles_upregulated |
| | | [cgc6390]:Cluster_C |
| | Interaction (178) |
| Map_info | Map | I | Position | 8.73905 | Error | 0.018869 |
| | Positive | Positive_clone | ZK1025 | Inferred_automatically | From sequence, transcript, pseudogene data |
| | Mapping_data | Pos_neg_data | 10949 |
| | | | 10950 |
| | | | 10951 |
| Reference | WBPaper00029153 |
| | WBPaper00031925 |
| | WBPaper00035152 |
| | WBPaper00039104 |
| | WBPaper00048269 |
| | WBPaper00051834 |
| | WBPaper00065106 |
| Method | Gene |
