Cbr-tra-2 encodes a plasma membrane protein that is orthologous to C. elegans TRA-2; as in C. elegans, loss of Cbr-tra-2 function results in incomplete sexual cell fate transformations of XX hermaphrodites to male fates, including a one-armed gonad containing only sperm, an abnormal male tail with incomplete sensory rays, and lack of male mating behavior.
Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in hermaphrodite germ-line sex determination and hermaphrodite somatic sex determination. Is an ortholog of C. elegans tra-2. In C. elegans, tra-2 is involved in developmental process involved in reproduction and oocyte fate determination.