WormBase Tree Display for Variation: WBVar00275589

WBVar00275589 Evidence: Paper_evidence: WBPaper00031485
  Name: Public_name: ed23
    HGVSg: chrII:g.5620403T>G
  Sequence_details: SMap: S_parent: Sequence: cb25.fpc2454a2
    Flanking_sequences: ccaagtacacaaagtttcaagttgctcaag tgcgtactcagaagaaccattcgagaaact
    Mapping_target: cb25.fpc2454a2
    Type_of_mutation: Substitution: a c
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis briggsae
    Laboratory: DP
    Status: Live
  Affects: Gene: WBGene00032357
    Transcript: CBG11194a.1 VEP_consequence: missense_variant
        VEP_impact: MODERATE
        HGVSc: CBG11194a.1:c.1760A>C
        HGVSp: CBP38209.1:p.Asp587Ala
        cDNA_position: 1760
        CDS_position: 1760
        Protein_position: 587
        Exon_number: 10/24
        Codon_change: gAt/gCt
        Amino_acid_change: D/A
      CBG11194b.1 VEP_consequence: missense_variant
        VEP_impact: MODERATE
        HGVSc: CBG11194b.1:c.1745A>C
        HGVSp: CBP41441.1:p.Asp582Ala
        cDNA_position: 1745
        CDS_position: 1745
        Protein_position: 582
        Exon_number: 10/24
        Codon_change: gAt/gCt
        Amino_acid_change: D/A
      CBG11194c.1 VEP_consequence: missense_variant
        VEP_impact: MODERATE
        HGVSc: CBG11194c.1:c.1745A>C
        HGVSp: CBP43518.1:p.Asp582Ala
        cDNA_position: 1745
        CDS_position: 1745
        Protein_position: 582
        Exon_number: 10/24
        Codon_change: gAt/gCt
        Amino_acid_change: D/A
  Description: Phenotype: WBPhenotype:0001277 Paper_evidence: WBPaper00031485
        Curator_confirmed: WBPerson2021
        Remark: Incomplete Tra, occasional Pvl. Complete rescue at 15C Paper_evidence: WBPaper00031485
            Curator_confirmed: WBPerson2021
        Penetrance: Incomplete: Paper_evidence: WBPaper00031485
              Curator_confirmed: WBPerson2021
        Recessive: Paper_evidence: WBPaper00031485
          Curator_confirmed: WBPerson2021
        Variation_effect: Probable_null_via_phenotype: Paper_evidence: WBPaper00031485
            Curator_confirmed: WBPerson2021
        Temperature_sensitive: Heat_sensitive: Paper_evidence: WBPaper00031485
              Curator_confirmed: WBPerson2021
    Phenotype_not_observed: WBPhenotype:0001414 Paper_evidence: WBPaper00031485
        Curator_confirmed: WBPerson2021
        Remark: Spontaneous XO ed23ts males mate successfully at the restrictive temperature Paper_evidence: WBPaper00031485
            Curator_confirmed: WBPerson2021
        Recessive: Paper_evidence: WBPaper00031485
          Curator_confirmed: WBPerson2021
        Variation_effect: Probable_null_via_phenotype: Paper_evidence: WBPaper00031485
            Curator_confirmed: WBPerson2021
  Reference: WBPaper00031485
  Method: Substitution_allele