WormBase Tree Display for Gene: WBGene00022348

WBGene00022348 SMap: S_parent: Sequence: Y82E9BR
  Identity: Version: 2
    Name: CGC_name: lelo-2 Person_evidence: WBPerson6609
            WBPerson1816
      Sequence_name: Y82E9BR.16
      Molecular_name: Y82E9BR.16a
        Y82E9BR.16a.1
        CE54578
        Y82E9BR.16b
        CE23368
        Y82E9BR.16b.1
      Other_name: CELE_Y82E9BR.16 Accession_evidence: NDB BX284603
      Public_name: lelo-2
    DB_info: Database: AceView gene 3C510
        WormQTL gene WBGene00022348
        WormFlux gene WBGene00022348
        NDB locus_tag CELE_Y82E9BR.16
        Panther gene CAEEL|WormBase=WBGene00022348|UniProtKB=Q9BKR9
          family PTHR24064
        NCBI gene 175300
        RefSeq protein NM_001421352.1
            NM_001381733.1
        TrEMBL UniProtAcc Q7Z1Q8
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:31:05 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 05 May 2023 12:43:53 WBPerson51134 Name_change: CGC_name: lelo-2
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: lelo
    Allele (270)
    Strain: WBStrain00037103
    RNASeq_FPKM (74)
    GO_annotation: 00083018
      00083019
      00126474
      00126475
      00126476
    Ortholog (43)
    Paralog (28)
    Structured_description: Automated_description: Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Expressed in germ line. Human ortholog(s) of this gene implicated in acute kidney failure. Is an ortholog of human SLC22A2 (solute carrier family 22 member 2). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:3021 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:10966)
  Molecular_info: Corresponding_CDS: Y82E9BR.16a
      Y82E9BR.16b
    Corresponding_CDS_history: Y82E9BR.16a:wp287
    Corresponding_transcript: Y82E9BR.16a.1
      Y82E9BR.16b.1
    Other_sequence (87)
    Associated_feature: WBsf666447
      WBsf981402
      WBsf991281
      WBsf991282
      WBsf991283
      WBsf1014223
      WBsf1014224
      WBsf226211
      WBsf226212
      WBsf226213
  Experimental_info: RNAi_result: WBRNAi00026599 Inferred_automatically: RNAi_primary
      WBRNAi00058587 Inferred_automatically: RNAi_primary
      WBRNAi00019995 Inferred_automatically: RNAi_primary
    Expr_pattern (6)
    Microarray_results (30)
    Expression_cluster: WBPaper00005700:transmembrane_protein
      WBPaper00030922:glycosylated_protein
      WBPaper00032097:CGH-1-associated-mRNA
      WBPaper00032528:L3_enriched
      WBPaper00035073:mitochondria_protein
      WBPaper00038438:Harposporium_24hr_downregulated_RNAseq
      WBPaper00044501:gld-1_let-7_regulated
      WBPaper00044736:flat_dev_expression
      WBPaper00045521:Gender_Neutral
      WBPaper00045774:clk-1_downregulated
      WBPaper00048923:Aging_regulated
      WBPaper00048926:miaserin_upregulated_adult-day5
      WBPaper00048988:neuron_expressed
      WBPaper00049545:cco-1(RNAi)_downregulated
      WBPaper00049545:jmjd-3.1(+)_downregulated
      WBPaper00049545:sur-5p-jmjd-1.2(+)_downregulated
      WBPaper00050412:cco-1(RNAi)_downregulated_N2
      WBPaper00050488:20C_vs_25C_regulated_N2_adult
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00051245:cytoplasm_specific
      WBPaper00051245:epidermis_cytoplasm_expressed
      WBPaper00051245:intestine_cytoplasm_expressed
      WBPaper00051558:aging_regulated
      WBPaper00053289:DREAM-target
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053388:dauer_regulated_Cluster4
      WBPaper00053615:SMO-1_target
      WBPaper00055354:Rifampicin-Allantoin_upregulated
      WBPaper00055648:germline_expressed
      WBPaper00055971:nhl-2(ok818)_25C_upregulated
      WBPaper00056034:pals-22(jy3)_upregulated
      WBPaper00056284:ints-1(RNAi)_upregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
      WBPaper00056471:S.aureus-4h_upregulated_N2
      WBPaper00056718:F01D4.5(baf20)_downregulated
      WBPaper00057288:Cold_upregulated_transcript
      WBPaper00057288:iff-1(RNAi)_upregulated_transcript
      WBPaper00058598:sin-3(tm1276)_upregulated
      WBPaper00058958:100mGy-irradiation-72h_upregulated
      WBPaper00059356:BAZ-2_SET-6_interacting
      WBPaper00060661:sensory-neuron_depleted
      WBPaper00060683:hlh-11(ko1)_downregulated
      WBPaper00060811:L1_vs_adult_upregulated_neural
      WBPaper00061203:let-418(n3536)_downregulated
      WBPaper00061203:sin-3(tm1276)_downregulated
      WBPaper00061203:spr-1(ok2144)_downregulated
      WBPaper00061340:G2_and_W_blasts
      WBPaper00061340:Parent_of_hyp3_ILsoDx
      WBPaper00061439:unc-30(ok613)_upregulated
      WBPaper00061527:C30H6.7-Y106G6H.5_2231
      WBPaper00061530:nhr-49(e2144)_upregulated
      WBPaper00061902:CAMT-1_interacting
      WBPaper00062056:lin-15B(n744)_upregulated
      WBPaper00062159:hda-2(ok1479)_downregulated
      WBPaper00062193:skn-1(RNAi)_upregulated
      WBPaper00062590:Aging_upregulated_body-wall-muscle
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00064071:NHR-49_interacting
      WBPaper00064315:mes-3(bn199)_downregulated_PGCs
      WBPaper00064315:mrg-1(qa6200)_downregulated_PGCs
      WBPaper00064494:postdauer_upregulated_AWA
      WBPaper00064539:nhr-114(gk849)_upregulated
      WBPaper00064716:paraquat_upregulated
      WBPaper00065096:Day10_vs_Day1_upregulated
      WBPaper00065120:body-muscle-transcriptome
      WBPaper00065258:anchor-cell_depleted
      WBPaper00065945:epidermis-rpoa-2(-)_upregulated_protein
      cgc4489_group_3
      cgc4489_group_8
      WBPaper00005124:estrogen_10-5M_regulated
      WBPaper00005124:progesterone_10-7M_regulated
      WBPaper00024393:strongly_regulated_dauer_genes
      WBPaper00025032:cluster_3
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00026980:intestine_enriched
      WBPaper00034739:RIL17moreRIL14
      WBPaper00035504:daf-2(e1370)_upregulated
      WBPaper00036123:Cadmium_regulated
      WBPaper00036286:Pattern_B
      WBPaper00038231:Cry5B_1.5-fold_downregulated
      WBPaper00038427:lin-54_embryo_changed
      WBPaper00041606:CE_B.thuringiensis-DB27_regulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00044091:Bpseudomallei_repressed_12h
      WBPaper00047070:N2_UV_upregulated
      WBPaper00053236:Starvation_regulated_GR1307
      WBPaper00053236:Starvation_regulated_N2
      [cgc5767]:cluster_8
      [cgc5767]:expression_class_E
      [cgc5767]:expression_class_ET
      [cgc5767]:expression_class_ET_max(66_min)
      [cgc5767]:expression_class_E_pi(23_min)
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_MD
      [cgc5767]:expression_class_ME
      [cgc5767]:expression_class_MET
    Interaction: WBInteraction000468759
      WBInteraction000551596
      WBInteraction000581274
  Map_info: Map: III Position: -21.8577
    Positive: Positive_clone: Y82E9BR Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00038491
    WBPaper00055090
    WBPaper00061547
    WBPaper00064064
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene