WormBase Tree Display for Gene: WBGene00022076

WBGene00022076 SMap: S_parent: Sequence: Y69A2AR
  Identity: Version: 2
    Name: CGC_name: daao-1 Person_evidence: WBPerson11473
      Sequence_name: Y69A2AR.5
      Molecular_name: Y69A2AR.5
        Y69A2AR.5.1
        CE36371
      Other_name: CELE_Y69A2AR.5 Accession_evidence: NDB BX284604
      Public_name: daao-1
    DB_info: Database (12)
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:31:05 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 29 Apr 2010 16:21:40 WBPerson2970 Name_change: CGC_name: daao-1
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: daao
    Allele (82)
    RNASeq_FPKM (74)
    GO_annotation (15)
    Ortholog (40)
    Paralog: WBGene00008127 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00017565 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00017648 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
    Structured_description: Concise_description: daao-1 encodes a D-amino acid oxidase (DAAO); recombinant DAOO-1 has DAAO activity on neutral and basic D-amino acid substrates (e.g., D-alanine or D-methionine, and D-arginine), with highest catalytic efficiency on D-arginine; since the C-terminal residues of DAAO-1 match the PTS1 consensus sequence, DAAO-1 is predicted to be peroxisomal. Paper_evidence: WBPaper00028859
          Curator_confirmed: WBPerson1843
            WBPerson567
          Date_last_updated: 25 May 2010 00:00:00
      Automated_description: Enables D-amino-acid oxidase activity. Involved in obsolete oxidation-reduction process. Predicted to be located in cytoplasm. Expressed in intestinal cell. Human ortholog(s) of this gene implicated in schizophrenia. Is an ortholog of human DDO (D-aspartate oxidase). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:5419 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2671)
  Molecular_info: Corresponding_CDS: Y69A2AR.5
    Corresponding_transcript: Y69A2AR.5.1
    Other_sequence: ASC01246_1
      JI225847.1
      Tcir_isotig12739
      CBC04024_1
    Associated_feature: WBsf645842
      WBsf995728
      WBsf228037
  Experimental_info: RNAi_result: WBRNAi00021313 Inferred_automatically: RNAi_primary
      WBRNAi00058054 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr9985
      Expr1017865
      Expr1161471
      Expr2010756
      Expr2028993
    Drives_construct: WBCnstr00014989
      WBCnstr00024352
    Construct_product: WBCnstr00024352
    Microarray_results (19)
    Expression_cluster: WBPaper00033065:isp-1-1(qm150)_upregulated
      WBPaper00037682:sma-2_downregulated
      WBPaper00037950:A-class-motor-neurons_L1-larva_expressed
      WBPaper00037950:all-neurons_L1-larva_expressed
      WBPaper00037950:bodywall-muscle_L1-larva_expressed
      WBPaper00037950:coelomocytes_L1-larva_expressed
      WBPaper00037950:coelomocytes_L2-larva_expressed
      WBPaper00037950:dopaminergic-neurons_L1-larva_expressed
      WBPaper00037950:excretory-cell_L2-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
      WBPaper00037950:germline-precursors_blastula-embryo_expressed
      WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed
      WBPaper00037950:hypodermis_L1-larva_expressed
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00037950:intestine_L2-larva_expressed
      WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
      WBPaper00038168:lin-15B(n744)_downregulated
      WBPaper00038438:P.lumniescens_24hr_downregulated_TilingArray
      WBPaper00038438:S.marcescens_24hr_upregulated_RNAseq
      WBPaper00042194:nhr-114(RNAi)_downregulated
      WBPaper00042561:smgl-1(RNAi)_downregulated
      WBPaper00044030:nhr-8(hd117)_downregulated
      WBPaper00044246:pgrn-1_ced-3_ced-1_downregulated
      WBPaper00044316:CH3HgCl_7.5uM_downregulated
      WBPaper00044426:rotenone_24h_upregulated
      WBPaper00044656:tatn-1(qd182)_upregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00045017:blmp-1(tm548)_downregulated
      WBPaper00045050:csr-1(hypomorph)_downregulated
      WBPaper00045314:S.aureus-induced_N2
      WBPaper00045390:tunicamycin_downregulated
      WBPaper00045401:N.parisii_40h_downregulated
      WBPaper00045401:N.parisii_64h_downregulated
      WBPaper00045571:germline-ablation_upregulated
      WBPaper00045774:clk-1_upregulated
      WBPaper00045774:clk-1_upregulated_CoQ10_independent
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
      WBPaper00048971:daf-16(mgDf50)_upregulated_L1
      WBPaper00049018:swsn-2.2(RNAi)_downregulated
      WBPaper00049334:CE_intestine_enriched
      WBPaper00049484:elt-2(RNAi)_downregulated_L4
      WBPaper00049498:npr-1(ur89)_regulated_8
      WBPaper00049635:dop-1(vs100)_downregulated
      WBPaper00049942:HeatShock_downregulated_hsf-1(+)
      WBPaper00049942:HeatShock_downregulated_hsf-1(RNAi)
      WBPaper00050080:rbr-2(tm3141)_upregulated
      WBPaper00050096:P.aeruginosa_downregulated
      WBPaper00050163:chd-3(eh4);let-418(RNAi)_upregulated_100-cell-embryo
      WBPaper00050163:chd-3(eh4)_downregulated_100-cell-embryo
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_adult_20C
      WBPaper00050504:hrp-2(RNAi)_downregulated
      WBPaper00050801:DAF-16_dauer_regulome
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00053020:sta-1(ok587)_downregulated
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053289:DREAM-target
      WBPaper00053295:lin-22(icb38)_downregulated
      WBPaper00053295:lin-22(ot267)_downregulated
      WBPaper00053302:stavudine_72h_regulated
      WBPaper00053308:SMG-2_associated_NMD(-)_unaltered_ClassII
      WBPaper00053402:his-3(RNAi)_downregulated
      WBPaper00053810:clk-1(qm30)_upregulated
      WBPaper00053810:daf-2(e1370)_upregulated
      WBPaper00053810:isp-1(qm150)_upregulated
      WBPaper00053810:nuo-6(qm200)_upregulated
      WBPaper00054758:alg-1(gk204)_downregulated
      WBPaper00054872:egl-9(sa307)_downregulated
      WBPaper00055013:hmg-3(bar24)_upregulated
      WBPaper00055060:flr-1(RNAi)_upregulated
      WBPaper00055137:S.maltophilia_downregulated
      WBPaper00055354:eat-2(ad1116)_upregulated
      WBPaper00055354:Psora_downregulated
      WBPaper00055354:Rifampicin_downregulated
      WBPaper00055386:eat-2(ad465)_downregulated
      WBPaper00055827:daf-2(e1370)_downregulated
      WBPaper00055862:antimycin_damt-1(gk961032)_regulated
      WBPaper00055897:heat-shock_downregulated
      WBPaper00055941:nuo-6(qm200);atfs-1(gk3094)_upregulated
      WBPaper00055941:nuo-6(qm200)_upregulated
      WBPaper00055971:nhl-2(ok818)_20C_upregulated
      WBPaper00055971:nhl-2(ok818)_25C_upregulated
      WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
      WBPaper00056090:E.faecalis_upregulated_N2
      WBPaper00056139:soil-microbiota_downregulated
      WBPaper00056167:Cry5B_upregulated
      WBPaper00056169:rrf-3(pk1426)_downregulated_L3
      WBPaper00056284:ints-11(RNAi)_downregulated
      WBPaper00056326:zip-3(gk3164)_upregulated_P.aeruginosa-infected
      WBPaper00056443:DietaryRestriction_downregulated
      WBPaper00056443:sek-1(km4)_downregulated
      WBPaper00056471:S.aureus-4h_upregulated_N2
      WBPaper00056550:ceh-60(ok1485)_upregulated_AdultDay1
      WBPaper00056550:ceh-60(ok1485)_upregulated_AdultDay4
      WBPaper00056586:kri-1(ok1251)_downregulated
      WBPaper00056586:mpk-2(ok219)_downregulated
      WBPaper00056809:smn-1(ok355)_downregulated
      WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
      WBPaper00057006:DietaryRestriction_upregulated
      WBPaper00057068:Cadmium_downregulated
      WBPaper00057068:ints-4(RNAi)_downregulated
      WBPaper00057265:metaformin_upregulated_OP50
      WBPaper00057265:metaformin_upregulated_OP50-MR
      WBPaper00058598:mex-3(eu149)_upregulated
      WBPaper00058711:skn-1(lax188)_downregulated
      WBPaper00058711:wdr-5(ok1417)_downregulated
      WBPaper00059191:hsp-16.2p-LIN-29_downregulated
      WBPaper00059253:stearic-acid_upregulated
      WBPaper00059253:sucrose_stearic-acid_upregulated
      WBPaper00059253:sucrose_upregulated
      WBPaper00059328:mrps-5(RNAi)_upregulated_mRNA
      WBPaper00059605:mut-16(pk710)_downregulated
      WBPaper00059754:C.neoformans_H99_upregulated
      WBPaper00059754:E.faecalis_OG1RF_upregulated
      WBPaper00059839:S.maltophilia_regulated
      WBPaper00060014:set-2(zr2012)_upregulated
      WBPaper00060100:SiNP_downregulated_mRNA
      WBPaper00060273:isp-1(qm150)_upregulated
      WBPaper00060358:B.thuringiensis_non-pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060399:CoCl2_6hr_downregulated_N2
      WBPaper00060526:plp-1(ok2155)_downregulated
      WBPaper00060661:sensory-neuron_depleted
      WBPaper00060911:prx-5(RNAi)_upregulated_mRNA
      WBPaper00061081:E.faecalis_upregulated_N2
      WBPaper00061274:microgravity_downregulated
      WBPaper00061341:28C_48h_downregulated
      WBPaper00061439:unc-30(ok613)_upregulated_P.aeruginosa-infection
      WBPaper00061466:nath-10(icb99)_upregulated
      WBPaper00061479:hda-1(ne4752)_upregulated
      WBPaper00061479:mep-1(ne4629)_upregulated
      WBPaper00061527:srj-21-srh-32
      WBPaper00061530:nhr-49(e2144)_downregulated
      WBPaper00061753:csr-1(tor159)_upregulated_25C
      WBPaper00061952:daf-18(yh1)_downregulated
      WBPaper00061995:mter-4(syb3662syb3403)_upregulated
      WBPaper00062056:lin-36(we31)_downregulated
      WBPaper00062146:MOG-7-degron_1h_regulated
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062167:mbl-1(tm1563)_downregulated
      WBPaper00062193:daf-16(RNAi)_downregulated
      WBPaper00062193:skn-1(RNAi)_downregulated
      WBPaper00062197:mec-8_upregulated_TRN
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062345:bortezomib_4h_downregulated_N2
      WBPaper00062345:bortezomib_4h_downregulated_zip-1(jy13)
      WBPaper00062354:H.zoospora_6h_regulated
      WBPaper00062440:crh-1(n3315)_downregulated
      WBPaper00062440:crh-1(syb385)_downregulated
      WBPaper00062684:pathogen_upregulated_N2
      WBPaper00064005:starvation_downregulated_aptf-1(gk794)_mRNA
      WBPaper00064005:starvation_downregulated_N2_mRNA
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064229:B.thuringiensis-Cry5Ba_upregulated
      WBPaper00064532:pals-22(jy3)_downregulated
      WBPaper00064532:pals-25(icb98)_upregulated
      WBPaper00064632:daf-2(e1370)_upregulated_intestine
      WBPaper00064716:paraquat_downregulated
      WBPaper00064727:daf-2(e1370)_upregulated
      WBPaper00064933:bcf-1(ylf1)_downregulated_transcript
      WBPaper00065005:sams-5(RNAi)_downregulated
      WBPaper00065086:JU1400_N.ausubeli_regulated
      WBPaper00065086:JU1400_N.ferruginous_regulated
      WBPaper00065086:N2_N.ausubeli_regulated
      WBPaper00065272:dhgd-1(tm6671)_upregulated
      WBPaper00065392:Lb.delbrueckii_upregulated
      WBPaper00065392:Lb.rhamnosus_upregulated
      WBPaper00065835:Day11_vs_Day1_downregulated
      WBPaper00065835:mtH2S-AP39-D0-treatment_upregulated_Day11
      WBPaper00065877:rege-1(imm070)_downregulated_OP50
      WBPaper00065945:epidermis-rpoa-2(-)_upregulated_protein
      WBPaper00065975:P-body_vs_WholeAnimal_depleted
      WBPaper00065984:pals-17(syb3980)_downregulated
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00066005:RAGA-1_degradation_somatic_upregulated
      WBPaper00066062:xrep-4(lax137)_upregulated
      WBPaper00066146:germline-inx-14(RNAi)_upregulated_PA14
      WBPaper00066232:hsf-1(RNAi)_downregulated_WT
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00036286:Pattern_I
      WBPaper00040116:pRJ-FR.5_up_regulated
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00041939:control_vs_UVC-exposed_51h
      WBPaper00041960:N2_fasting_upregulated_9hto12h
      WBPaper00041960:N2_fasting_upregulated_anytime
      WBPaper00044091:Bpseudomallei_repressed_8h
      WBPaper00044091:Bpseudomallei_repressed_12h
      [cgc6390]:Cluster_A
    Interaction: WBInteraction000114308
  Map_info: Map: IV Position: -6.99235 Error: 0.026989
    Positive: Positive_clone: Y69A2AR Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00028859
    WBPaper00038491
    WBPaper00040844
    WBPaper00051709
    WBPaper00053154
    WBPaper00055090
    WBPaper00060161
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene