WormBase Tree Display for Gene: WBGene00020453

WBGene00020453 SMap: S_parent: Sequence: CHROMOSOME_III
  Identity: Version: 2
    Name: CGC_name: fbxa-55 Person_evidence: WBPerson655
      Sequence_name: T12B5.6
      Molecular_name: T12B5.6b
        T12B5.6a
        CE39403
        T12B5.6c
        CE51680
        T12B5.6b.1
        T12B5.6c.1
      Other_name: CELE_T12B5.6 Accession_evidence: NDB BX284603
      Public_name: fbxa-55
    DB_info: Database: WormQTL gene WBGene00020453
        WormFlux gene WBGene00020453
        NDB locus_tag CELE_T12B5.6
        Panther gene CAEEL|WormBase=WBGene00020453|UniProtKB=Q2WF55
          family PTHR23015
        NCBI gene 188445
        RefSeq protein NM_001047409.4
            NM_001330938.4
            NR_138510.1
        TREEFAM TREEFAM_ID TF322360
        TrEMBL UniProtAcc A0A163VTZ6
            Q2WF55
        UniProt_GCRP UniProtAcc Q2WF55
        RNAcentral URSid URS00009E1D4F
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:31:03 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 12 Dec 2005 15:18:56 WBPerson2970 Name_change: CGC_name: fbxa-55
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: fbxa
    Allele (125)
    RNASeq_FPKM (74)
    Ortholog (25)
    Paralog (222)
    Structured_description: Concise_description: This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction. Paper_evidence: WBPaper00012854
          Curator_confirmed: WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Enriched in AFD; ASER; and intestine based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by twelve chemicals including rotenone; metformin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; FTH domain; and F-box A protein FB224. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: T12B5.6b
      T12B5.6c
    Corresponding_CDS_history: T12B5.6:wp151
      T12B5.6a:wp253
    Corresponding_transcript: T12B5.6a
      T12B5.6b.1
      T12B5.6c.1
    Other_sequence: Oden_isotig22831
    Associated_feature: WBsf991189
      WBsf1014150
  Experimental_info: RNAi_result: WBRNAi00035506 Inferred_automatically: RNAi_primary
      WBRNAi00018634 Inferred_automatically: RNAi_primary
      WBRNAi00053190 Inferred_automatically: RNAi_primary
      WBRNAi00006619 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1156782
      Expr2011557
      Expr2029795
    Drives_construct: WBCnstr00025127
    Construct_product: WBCnstr00025127
    Microarray_results (20)
    Expression_cluster: WBPaper00031040:TGF-beta_adult_upregulated
      WBPaper00032425:down_in_rde-4
      WBPaper00033065:cyc-1(RNAi)_upregulated
      WBPaper00038438:Harposporium_24hr_upregulated_RNAseq
      WBPaper00038438:S.marcescens_24hr_downregulated_TilingArray
      WBPaper00042561:smg-2(RNAi)_upregulated
      WBPaper00042561:smgl-1(RNAi)_upregulated
      WBPaper00044037:eat-2_upregulated
      WBPaper00044426:rotenone_24h_upregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00045316:prg-1_upregulated_L4
      WBPaper00045618:fbf-1_upregulated
      WBPaper00048988:daf-2(e1370)_daf-16(mu86)_downregulated_neuron
      WBPaper00048988:daf-2(e1370)_downregulated_neuron
      WBPaper00048988:neuron_expressed
      WBPaper00049334:CE_intestine_enriched
      WBPaper00050344:AFD-neuron_enriched
      WBPaper00050344:ASER-neuron_enriched
      WBPaper00050370:dpy-21(e428)_L3_upregulated
      WBPaper00050488:20C_vs_25C_regulated_N2_adult
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_adult_25C
      WBPaper00050488:N2_vs_mir-34(OverExpression)_regulated_adult_25C
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050990:intestine_expressed
      WBPaper00050990:seam_expressed
      WBPaper00051039:intestine_enriched
      WBPaper00051404:alg-5(ram2)_downregulated
      WBPaper00051558:aging_regulated
      WBPaper00052884:emb-4(hc60)_downregulated
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053606:elt-2(ca15)_vs_elt-2(ca15);elt-7(tm840)_doenregulated
      WBPaper00053606:N2_vs_elt-2(ca15);elt-7(tm840)_downregulated
      WBPaper00053810:nuo-6(qm200)_upregulated
      WBPaper00053909:N2_vs_CB4856_upregulated
      WBPaper00055060:flr-1(RNAi)_upregulated
      WBPaper00055354:Rapamycin-Metformin_downregulated
      WBPaper00055354:Rifampicin-Allantoin_downregulated
      WBPaper00055827:daf-2(e1370)_upregulated
      WBPaper00056034:pals-22(jy3)_upregulated
      WBPaper00056034:pals-25(jy9)_upregulated
      WBPaper00056139:soil-microbiota_downregulated
      WBPaper00056161:male_enriched_siRNA
      WBPaper00056284:ints-1(RNAi)_upregulated
      WBPaper00056443:sek-1(km4)_upregulated
      WBPaper00056471:S.aureus-4h_upregulated_N2
      WBPaper00057006:DietaryRestriction_upregulated
      WBPaper00058711:paraquat_downregulated
      WBPaper00058711:wdr-5(ok1417)_downregulated
      WBPaper00058725:sftb-1(cer6)_upregulated
      WBPaper00058948:PA14_downregulated
      WBPaper00058958:10mGy-irradiation-72h_downregulated
      WBPaper00059356:BAZ-2_SET-6_interacting
      WBPaper00059664:srbc-48(ac23)_upregulated
      WBPaper00059839:S.maltophilia_regulated
      WBPaper00059987:Wounding_upregulated
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060661:sensory-neuron_depleted
      WBPaper00061341:28C_48h_downregulated
      WBPaper00061439:unc-30(ok613)_downregulated
      WBPaper00061439:unc-30(ok613)_downregulated_P.aeruginosa-infection
      WBPaper00061527:172183_at-176110_at
      WBPaper00061530:nhr-49(e2144)_upregulated
      WBPaper00061653:alh-4(hj221)_downregulated
      WBPaper00062184:PA14_upregulated
      WBPaper00062193:skn-1(RNAi)_downregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062672:let-418(n3536)dcp-66(RNAi)_downregulated
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064532:pals-22(jy3)_upregulated
      WBPaper00064716:paraquat_downregulated
      WBPaper00064939:vit-5(RNAi)_upregulated
      WBPaper00065086:JU1400_N.ferruginous_regulated
      WBPaper00065841:48_0
      WBPaper00065975:P-body_vs_WholeAnimal_depleted
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00066110:Cisplatin_upregulated_diploid
      WBPaper00066110:Doxorubicin_upregulated_diploid
      WBPaper00066232:ash-2(RNAi)_downregulated_WT
      WBPaper00066232:hsf-1(RNAi)_upregulated_ash-2
      WBPaper00024671:AFD_AWB_vs_unsorted_downregulated
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00027111:eri-1(mg366)_upregulated
      WBPaper00027111:rde-3(r459)_downregulated
      WBPaper00029437:dcr-1_upregulated
      WBPaper00029437:rde-4_upregulated
      WBPaper00030985:Erwinia_carotovora_downregulated
      WBPaper00034661:AgNPs_downregulated
      WBPaper00034739:N2moreDR1350
      WBPaper00034739:RIL17moreRIL14
      WBPaper00034757:up_by_oxidative_stress
      WBPaper00035227:heat_shock_regulated
      WBPaper00035873:dpy-10_regulated
      WBPaper00036123:Atrazine_regulated
      WBPaper00037704:ABZ_up_regulated
      WBPaper00038172:tax-6null_up_regulated
      WBPaper00040603:tdp-1(lf)_up_vs_N2_FC_1.2
      WBPaper00040858:eQTL_age_regulated_developing
      WBPaper00040858:eQTL_regulated_aging
      WBPaper00040858:eQTL_regulated_juvenile
      WBPaper00040858:eQTL_regulated_old
      WBPaper00040858:eQTL_regulated_reproductive
      WBPaper00040963:TA100_up
      WBPaper00040963:TA200_up
      WBPaper00040963:TA300_up
      WBPaper00041002:HQ_3d_2.0mM_Up
      WBPaper00041370:spg-7(RNAi)_upregulated
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:control_vs_EtBr-exposed_51h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00041939:control_vs_UVC-exposed_51h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00042331:a-SWCNTs_downregulated
      WBPaper00045263:0.1mM-paraquat_downregulated
      WBPaper00047070:xpa-1_UV_upregulated
      WBPaper00050515:nipi-3(fr4)_upregulated
      WBPaper00053236:daf-16(mgDF50)_regulated_Starved
      WBPaper00053236:Starvation_regulated_GR1307
      WBPaper00053236:Starvation_regulated_N2
      WBPaper00057098:SiO2-nanoparticles_upregulated
      [cgc6390]:mixed_spermatogenesis-somatic
    Interaction (27)
  Map_info: Map: III Position: -25.0866 Error: 0.003123
    Positive: Positive_clone: T12B5 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00012854
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene