WormBase Tree Display for Gene: WBGene00020397
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| WBGene00020397 | SMap | S_parent | Sequence | T10B11 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | pcbd-1 | Person_evidence | WBPerson384 | |||||
| Sequence_name | T10B11.1 | ||||||||
| Molecular_name | T10B11.1 | ||||||||
| T10B11.1.1 | |||||||||
| CE39768 | |||||||||
| Other_name | CELE_T10B11.1 | Accession_evidence | NDB | BX284601 | |||||
| Public_name | pcbd-1 | ||||||||
| DB_info | Database (13) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:31:03 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 28 Sep 2005 14:40:43 | WBPerson2970 | Name_change | CGC_name | pcbd-1 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | pcbd | ||||||||
| Allele (17) | |||||||||
| Strain | WBStrain00024122 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00098023 | ||||||||
| 00098024 | |||||||||
| 00098025 | |||||||||
| 00098026 | |||||||||
| 00125037 | |||||||||
| 00125038 | |||||||||
| Ortholog (36) | |||||||||
| Structured_description | Concise_description | pcbd-1 is orthologous to the human gene PTERIN-4-ALPHA-CARBINOLAMINE DEHYDRATASE (PCBD or TCF1; OMIM:126090), which when mutated leads to hyperphenylalaninemia with primapterinuria. | Person_evidence | WBPerson384 | |||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson1823 | |||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 24 May 2010 00:00:00 | ||||||||
| Automated_description | Predicted to enable 4-alpha-hydroxytetrahydrobiopterin dehydratase activity. Predicted to be involved in tetrahydrobiopterin biosynthetic process. Expressed in head; hypodermis; neurons; and pharyngeal muscle cell. Human ortholog(s) of this gene implicated in BH4-deficient hyperphenylalaninemia D. Is an ortholog of human PCBD1 (pterin-4 alpha-carbinolamine dehydratase 1). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0081131 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:8646) | ||||
| Molecular_info | Corresponding_CDS | T10B11.1 | |||||||
| Corresponding_CDS_history | T10B11.1:wp154 | ||||||||
| Corresponding_transcript | T10B11.1.1 | ||||||||
| Other_sequence (73) | |||||||||
| Associated_feature | WBsf643418 | ||||||||
| WBsf655782 | |||||||||
| WBsf217926 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00052994 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00081099 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00004194 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00035408 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00117094 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr11445 | ||||||||
| Expr12167 | |||||||||
| Expr1027403 | |||||||||
| Expr1038892 | |||||||||
| Expr1156597 | |||||||||
| Expr2014773 | |||||||||
| Expr2033007 | |||||||||
| Drives_construct | WBCnstr00020338 | ||||||||
| WBCnstr00020345 | |||||||||
| WBCnstr00025171 | |||||||||
| Construct_product | WBCnstr00025171 | ||||||||
| Microarray_results (18) | |||||||||
| Expression_cluster (142) | |||||||||
| Interaction (16) | |||||||||
| Map_info | Map | I | Position | 1.5698 | Error | 0.011368 | |||
| Positive | Positive_clone | T10B11 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 5509 | |||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00034518 | ||||||||
| WBPaper00034662 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00046585 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00064339 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
