WormBase Tree Display for Gene: WBGene00020382

WBGene00020382 SMap: S_parent: Sequence: T09B4
  Identity: Version: 1
    Name: Sequence_name: T09B4.8
      Molecular_name: T09B4.8
        T09B4.8.1
        CE33176
      Other_name: CELE_T09B4.8 Accession_evidence: NDB BX284601
      Public_name: T09B4.8
    DB_info: Database: AceView gene 1G742
        WormQTL gene WBGene00020382
        WormFlux gene WBGene00020382
        NDB locus_tag CELE_T09B4.8
        Panther gene CAEEL|WormBase=WBGene00020382|UniProtKB=O02158
          family PTHR45688
        NCBI gene 172301
        RefSeq protein NM_059376.11
        TREEFAM TREEFAM_ID TF105945
        TrEMBL UniProtAcc O02158
        UniProt_GCRP UniProtAcc O02158
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:31:03 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
    Status: Live
  Gene_info: Biotype: SO:0001217
    Allele (22)
    Strain: WBStrain00001402
      WBStrain00002393
    RNASeq_FPKM (74)
    GO_annotation: 00026651
      00026652
      00026653
      00026654
      00026655
      00026656
      00125016
      00125017
    Ortholog (37)
    Paralog: WBGene00001794 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00015814 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00020139 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Automated_description: Predicted to enable alanine-glyoxylate transaminase activity. Predicted to be involved in L-alanine catabolic process, by transamination and glyoxylate catabolic process. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); atrial fibrillation; and mild cognitive impairment. Is an ortholog of human AGXT2 (alanine--glyoxylate aminotransferase 2). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:6000 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:14412)
      DOID:3669 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:14412)
      DOID:3526 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:14412)
      DOID:0080832 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:14412)
      DOID:0060224 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:14412)
      DOID:3393 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:14412)
      DOID:10763 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:14412)
  Molecular_info: Corresponding_CDS: T09B4.8
    Corresponding_CDS_history: T09B4.8:wp92
    Corresponding_transcript: T09B4.8.1
    Other_sequence (32)
    Associated_feature: WBsf649221
      WBsf983849
      WBsf983850
      WBsf1009909
      WBsf219546
      WBsf219547
      WBsf219548
  Experimental_info: RNAi_result: WBRNAi00084404 Inferred_automatically: RNAi_primary
      WBRNAi00024105 Inferred_automatically: RNAi_primary
      WBRNAi00023307 Inferred_automatically: RNAi_primary
      WBRNAi00004184 Inferred_automatically: RNAi_primary
      WBRNAi00084382 Inferred_automatically: RNAi_primary
      WBRNAi00023583 Inferred_automatically: RNAi_primary
      WBRNAi00052937 Inferred_automatically: RNAi_primary
      WBRNAi00117093 Inferred_automatically: RNAi_primary
      WBRNAi00023817 Inferred_automatically: RNAi_primary
      WBRNAi00033469 Inferred_automatically: RNAi_primary
    Expr_pattern: Chronogram880
      Chronogram1492
      Expr6648
      Expr6649
      Expr1015137
      Expr1038883
      Expr1156538
      Expr2006034
      Expr2024249
    Drives_construct: WBCnstr00002292
      WBCnstr00004293
      WBCnstr00025177
    Construct_product: WBCnstr00025177
    Microarray_results (17)
    Expression_cluster: WBPaper00029359_1166
      WBPaper00029359_1197
      WBPaper00029359_1291
      WBPaper00029359_1320
      WBPaper00029359_1326
      WBPaper00029359_1345
      WBPaper00029359_1439
      WBPaper00029359_1458
      WBPaper00029359_1519
      WBPaper00029359_1546
      WBPaper00029359_1549
      WBPaper00029359_1557
      WBPaper00029359_1599
      WBPaper00029359_1618
      WBPaper00031040:TGF-beta_adult_upregulated
      WBPaper00032031:DConiospora_downregulated_cDNA_12h
      WBPaper00032425:up_in_rde-4
      WBPaper00032528:L3_enriched
      WBPaper00035073:mitochondria_protein
      WBPaper00037047:insoluble_protein
      WBPaper00037950:bodywall-muscle_L2-larva_expressed
      WBPaper00037950:bodywall-muscle_larva_enriched
      WBPaper00037950:bodywall-muscle_larva_SelectivelyEnriched
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:hypodermis_L1-larva_expressed
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00037950:intestine_L2-larva_expressed
      WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00038438:D.coniospora_12hr_downregulated_RNAseq
      WBPaper00038438:S.marcescens_24hr_upregulated_RNAseq
      WBPaper00044501:gld-1_let-7_regulated
      WBPaper00044656:tatn-1(qd182)_upregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00044746:aging_downregulated_HeatShock
      WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_upregulated
      WBPaper00045390:tunicamycin_upregulated
      WBPaper00045417:128Q-huntingtin_upreglated
      WBPaper00045521:Spermatogenic
      WBPaper00045774:clk-1_downregulated
      WBPaper00045934:wrn-1(gk99)_upregulated
      WBPaper00046012:tdp-1(ok803)_upregulated
      WBPaper00046217:clk-1(qm30)_downregulated
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
      WBPaper00048926:miaserin_upregulated_adult-day5
      WBPaper00048988:neuron_expressed
      WBPaper00049018:swsn-2.2(RNAi)_upregulated
      WBPaper00049217:DAF-16_downregulated
      WBPaper00049498:npr-1(ur89)_regulated_3
      WBPaper00049545:cco-1(RNAi)_downregulated
      WBPaper00049545:sur-5p-jmjd-1.2(+)_downregulated
      WBPaper00049942:HeatShock_downregulated_hsf-1(RNAi)
      WBPaper00049942:HeatShock_upregulated_hsf-1(+)
      WBPaper00049942:hsf-1(RNAi)_downregulated
      WBPaper00049954:BPS_upregulated
      WBPaper00050053:muscle_enriched_Day4
      WBPaper00050163:chd-3(eh4);let-418(RNAi)_upregulated_24-cell-embryo
      WBPaper00050344:ASER-neuron_enriched
      WBPaper00050412:cco-1(RNAi)_downregulated_N2
      WBPaper00050599:nicotine(0.01mM)_upregulated
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050726:starvation_regulated_LowSalt
      WBPaper00050801:DAF-16_dauer_regulome
      WBPaper00050859:upregulated_glh-1(gk100)_vs_control_day1-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day1-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00051555:atm-1(gk186)_regulated_protein
      WBPaper00051558:aging_regulated
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053295:lin-22(ot269)_downregulated
      WBPaper00053302:alovudine_24h_regulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053302:zidovudine_24h_regulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053388:dauer_regulated_Cluster1
      WBPaper00053599:female_vs_male_downregulated
      WBPaper00053599:oocyte_vs_mitosis_downregulated
      WBPaper00053810:daf-2(e1370)_downregulated
      WBPaper00053814:15C_downregulated_PY79
      WBPaper00054192:cold-shock_downregulated
      WBPaper00055354:Rapamycin_downregulated
      WBPaper00055354:Rifampicin_upregulated
      WBPaper00055804:FBF-1-FBF-2-associated_spermatogenic-enriched
      WBPaper00055971:nhl-2(ok818)_25C_downregulated
      WBPaper00056034:pals-22(jy3)_upregulated
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00056139:soil-microbiota_upregulated
      WBPaper00056161:male_enriched_siRNA
      WBPaper00056443:sek-1(km4)_upregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
      WBPaper00056471:S.aureus-4h_downregulated_N2
      WBPaper00056809:smn-1(ok355)_downregulated
      WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
      WBPaper00057041:spc-1(cas971)_upregulated
      WBPaper00057041:unc-70(cas983)_upregulated
      WBPaper00058598:sin-3(tm1276)_downregulated
      WBPaper00058691:cfp-1(tm6369)_downregulated
      WBPaper00058691:sin-3(tm1276)_downregulated
      WBPaper00058969:RIS_depleted
      WBPaper00059664:srbc-48(ac23)_upregulated
      WBPaper00059824:rnp-6(dh1127)_regulated_OP50
      WBPaper00059824:rnp-6(dh1127)_regulated_S.aureus
      WBPaper00059895:wounding_downregulated
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060661:sensory-neuron_depleted
      WBPaper00060909:atfs-1(cmh15)_downregulated
      WBPaper00061007:HB101_upregulated
      WBPaper00061203:let-418(n3536)_upregulated
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061203:spr-1(ok2144)_upregulated
      WBPaper00061340:Body_wall_muscle
      WBPaper00061340:BWM_anterior
      WBPaper00061340:BWM_far_posterior
      WBPaper00061341:28C_48h_downregulated
      WBPaper00061479:hda-1(ne4748)_upregulated
      WBPaper00061479:hda-1(ne4752)_upregulated
      WBPaper00061527:T24C12.3-C01G10.9
      WBPaper00061818:AFD_enriched_protein
      WBPaper00061818:ELKS-1_interacting
      WBPaper00061902:camt-1(ok515)_regulated_URX-AQR-PQR
      WBPaper00062325:muscle_enriched_coding-RNA
      WBPaper00062354:H.zoospora_6h_regulated
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00064005:starvation_upregulated_N2_mRNA
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064315:mes-3(bn199)_upregulated_EGCs
      WBPaper00064315:mes-4(bn73)_upregulated_EGCs
      WBPaper00064403:Heat-killed-E.Coli_upregulated
      WBPaper00064502:nhr-23(kry61);spe-44(fx110)_downregulated
      WBPaper00064716:paraquat_downregulated
      WBPaper00065096:Day10_vs_Day1_downregulated
      WBPaper00065096:npr-8(ok1439)_upregulated_Day1_25C
      WBPaper00065373:Cisplatin_downregulated_WT
      WBPaper00065835:Day5_vs_Day1_downregulated
      WBPaper00065835:Day11_vs_Day1_downregulated
      WBPaper00065841:11_0
      WBPaper00065975:P-body_vs_oocyte_depleted
      WBPaper00065975:P-body_vs_WholeAnimal_depleted
      cgc4489_group_8
      WBPaper00024393:strongly_regulated_dauer_genes
      WBPaper00025032:cluster_2
      WBPaper00025032:cluster_10
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00027342:alpha-Synuclein(WT)_upregulated
      WBPaper00031003:24hr_muscle_enriched
      WBPaper00031003:hlh_1_enriched
      WBPaper00031003:total_muscle_enriched
      WBPaper00031532:Larva_Pan_Neuronal_Depleted
      WBPaper00032948:FedUp
      WBPaper00034739:TreatmentAffectedGenes
      WBPaper00034757:down_by_oxidative_stress
      WBPaper00035873:dpy-10_regulated
      WBPaper00035873:osm-8_regulated
      WBPaper00038231:Cry5B_1.5-fold_downregulated
      WBPaper00038231:Cry5B_2-fold_downregulated
      WBPaper00040184:hcf-1down_sir-2.1down_daf-2down
      WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2
      WBPaper00040963:Q100_down
      WBPaper00040963:Q200_down
      WBPaper00041002:HF_3d_0.2mM_Up
      WBPaper00041002:HF_3d_2.0mM_Up
      WBPaper00041207:CE_dauer_down
      WBPaper00041606:CE_S.marcescens_regulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041906:I-3690_vs_OP50_3d
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_24h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041960:N2_fasting_upregulated_anytime
      WBPaper00042258:DA1877_upregulated_GravidAdult
      WBPaper00047070:N2_starvation_downregulated
      WBPaper00048989:N2_allantoin_upregulated
      WBPaper00053236:daf-16(mgDF50)_regulated_Starved
      WBPaper00053236:Starvation_regulated_GR1307
      WBPaper00053236:Starvation_regulated_N2
      [cgc5767]:cluster_5
      [cgc5767]:expression_class_E
      [cgc5767]:expression_class_E_pi(53_min)
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_ME
      [cgc6390]:Cluster_C
    Interaction (116)
  Map_info: Positive: Positive_clone: T09B4 Inferred_automatically: From sequence, transcript, pseudogene data
    Interpolated_map_position: I 0.850703
  Reference: WBPaper00038491
    WBPaper00055090
    WBPaper00064339
    WBPaper00065140
  Method: Gene