T07A9.9 encodes a GTPase with similarity to the mammalian CRFG proteins and Saccharomyces cerevisiae nucleolar NOG1 involved in biogenesis of the 60S ribosomal subunit; in C. elegans, T07A9.9 plays a role in regulating growth, development, lifespan, and fat metabolism; T07A9.9::GFP reporter fusions expressed ubiquitously throughout the life cycle and localizes to the nucleus; in intestinal cells, a T07A9.9 reporter fusion localizes to the nucleolus.
Predicted to enable GTPase activity and RNA binding activity. Involved in several processes, including determination of adult lifespan; negative regulation of lipid storage; and regulation of reproductive process. Located in nucleolus. Expressed in several structures, including excretory cell; germ cell; intestine; pharynx; and vulva. Is an ortholog of human GTPBP4 (GTP binding protein 4).
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.