WormBase Tree Display for Gene: WBGene00020109

WBGene00020109 SMap: S_parent: Sequence: R151
  Identity: Version: 2
    Name: CGC_name: der-2 Person_evidence: WBPerson2876
      Sequence_name: R151.6
      Molecular_name: R151.6
        R151.6.1
        CE39620
      Other_name: CELE_R151.6 Accession_evidence: NDB BX284603
      Public_name: der-2
    DB_info: Database: AceView gene 3I312
        WormQTL gene WBGene00020109
        WormFlux gene WBGene00020109
        NDB locus_tag CELE_R151.6
        Panther gene CAEEL|WormBase=WBGene00020109|UniProtKB=Q21997
          family PTHR11009
        NCBI gene 176018
        RefSeq protein NM_001392140.1
        SwissProt UniProtAcc Q21997
        TREEFAM TREEFAM_ID TF314715
        UniProt_GCRP UniProtAcc Q21997
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:31:02 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 02 Mar 2020 15:25:00 WBPerson1983 Name_change: CGC_name: der-2
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: der
    Allele (23)
    Strain: WBStrain00052444
    RNASeq_FPKM (74)
    GO_annotation (19)
    Contained_in_operon: CEOP3424
    Ortholog (40)
    Paralog: WBGene00000843 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
    Structured_description: Automated_description: Predicted to enable misfolded protein binding activity; signal recognition particle binding activity; and ubiquitin-specific protease binding activity. Involved in IRE1-mediated unfolded protein response. Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of Hrd1p ubiquitin ligase ERAD-L complex. Is an ortholog of human DERL2 (derlin 2). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: R151.6
    Corresponding_CDS_history: R151.6:wp153
    Corresponding_transcript: R151.6.1
    Other_sequence (31)
    Associated_feature: WBsf226933
      WBsf226934
  Experimental_info: RNAi_result (15)
    Expr_pattern: Expr1016417
      Expr1038745
      Expr1155622
      Expr2005658
      Expr2023874
    Drives_construct: WBCnstr00025369
    Construct_product: WBCnstr00025369
    Microarray_results (20)
    Expression_cluster: WBPaper00031040:TGF-beta_adult_downregulated
      WBPaper00032425:up_in_rde-4
      WBPaper00041506:EMS_enriched
      WBPaper00044426:rotenone_24h_upregulated
      WBPaper00044501:gld-1_let-7_regulated
      WBPaper00044736:flat_dev_expression
      WBPaper00045521:Gender_Neutral
      WBPaper00046887:WNT-target
      WBPaper00048762:FOG-3_associated
      WBPaper00048988:neuron_expressed
      WBPaper00049942:hsf-1(RNAi)_downregulated
      WBPaper00050344:AFD-neuron_enriched
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050990:intestine_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00051039:germline_enriched
      WBPaper00051245:epidermis_cytoplasm_expressed
      WBPaper00051245:intestine_cytoplasm_expressed
      WBPaper00051311:VGLN-1-interacting
      WBPaper00053184:sma-4(rax3)_downregulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053810:daf-2(e1370)_downregulated
      WBPaper00055354:Rapamycin-Metformin_upregulated
      WBPaper00055354:Rapamycin-Rifampicin-Allantoin_upregulated
      WBPaper00055354:Rapamycin-Rifampicin_upregulated
      WBPaper00055354:Rifampicin-Allantoin_upregulated
      WBPaper00055648:germline_expressed
      WBPaper00056165:MINA-1_interacting_mRNA
      WBPaper00056471:S.aureus-4h_downregulated_N2
      WBPaper00056868:P.aeruginosa_upregulated_smallRNA
      WBPaper00060100:SiNP_downregulated_mRNA
      WBPaper00061340:AMso_parent
      WBPaper00061341:28C_48h_downregulated
      WBPaper00061439:unc-30(ok613)_upregulated
      WBPaper00061527:cyy-1_3136-hcf-1_2478
      WBPaper00061527:pbs-3_18439-rpn-5
      WBPaper00062456:doxycycline_upregulated_CB4856_protein
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00064716:paraquat_upregulated
      WBPaper00064789:Day12_vs_Day1_downregulated_neuron
      WBPaper00025032:cluster_167
      WBPaper00025032:cluster_170
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00026980:intestine_enriched
      WBPaper00034661:AgNPs_upregulated
      WBPaper00034739:N2lessDR1350
      WBPaper00035905:FBF-1_Associated
      WBPaper00036286:Pattern_F
      WBPaper00041606:CE_B.thuringiensis-DB27_regulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h
      WBPaper00048637:lin-35(n745)_starvation_downregulated
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_MD
      [cgc5767]:expression_class_MD_pd(53_min)
      [cgc5767]:expression_class_MD_pd(66_min)
      [cgc5767]:expression_class_SM
      [cgc5767]:expression_class_SMD
    Interaction (18)
  Map_info: Map: III Position: -0.767964
    Positive: Positive_clone: R151 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (11)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene