WormBase Tree Display for Gene: WBGene00000843
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| WBGene00000843 | SMap | S_parent | Sequence | F25D7 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 3 | |||||||
| Name | CGC_name | cup-2 | Person_evidence | WBPerson170 | |||||
| Sequence_name | F25D7.1 | ||||||||
| Molecular_name | F25D7.1 | ||||||||
| F25D7.1.1 | |||||||||
| CE09629 | |||||||||
| Other_name | tag-352 | CGC_data_submission | |||||||
| der-1 | Paper_evidence | WBPaper00039837 | |||||||
| WBPaper00036076 | |||||||||
| CELE_F25D7.1 | Accession_evidence | NDB | BX284601 | ||||||
| Public_name | cup-2 | ||||||||
| DB_info | Database | AceView | gene | 1K976 | |||||
| WormQTL | gene | WBGene00000843 | |||||||
| WormFlux | gene | WBGene00000843 | |||||||
| NDB | locus_tag | CELE_F25D7.1 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00000843|UniProtKB=Q93561 | |||||||
| family | PTHR11009 | ||||||||
| NCBI | gene | 172915 | |||||||
| RefSeq | protein | NM_060320.8 | |||||||
| SwissProt | UniProtAcc | Q93561 | |||||||
| TREEFAM | TREEFAM_ID | TF354297 | |||||||
| UniProt_GCRP | UniProtAcc | Q93561 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:21 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 18 Aug 2005 16:46:43 | WBPerson2970 | Event | Acquires_merge | WBGene00009111 | ||||
| Name_change | Sequence_name | F25D7.1 | |||||||
| Other_name | tag-352 | ||||||||
| 3 | 18 Nov 2013 10:09:17 | WBPerson2970 | Name_change | Other_name | der-1 | ||||
| Acquires_merge | WBGene00009111 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | cup | ||||||||
| Allele (27) | |||||||||
| Strain | WBStrain00036267 | ||||||||
| WBStrain00008047 | |||||||||
| WBStrain00052443 | |||||||||
| WBStrain00052655 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (21) | |||||||||
| Ortholog (34) | |||||||||
| Paralog | WBGene00020109 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | cup-2 encodes a C. elegans Derlin ortholog; the primary phenotype of cup-2 animals is an accumulation of secreted GFP in the pseudocoelom, suggesting a decrease in, or the absence of, endocytosis in coelomocytes; CUP-2 localizes to endosomes and to the endoplasmic reticulum. | Paper_evidence | WBPaper00004883 | |||||
| WBPaper00033458 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 09 Apr 2014 00:00:00 | ||||||||
| Automated_description | Predicted to enable misfolded protein binding activity; signal recognition particle binding activity; and ubiquitin-specific protease binding activity. Involved in endocytosis and response to misfolded protein. Located in early endosome and perinuclear endoplasmic reticulum. Expressed widely. Is an ortholog of human DERL1 (derlin 1). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | F25D7.1 | |||||||
| Corresponding_transcript | F25D7.1.1 | ||||||||
| Other_sequence (55) | |||||||||
| Associated_feature | WBsf984995 | ||||||||
| WBsf984996 | |||||||||
| WBsf984997 | |||||||||
| WBsf984998 | |||||||||
| WBsf984999 | |||||||||
| WBsf1010541 | |||||||||
| WBsf1010542 | |||||||||
| WBsf220233 | |||||||||
| Experimental_info | RNAi_result (23) | ||||||||
| Expr_pattern | Expr8719 | ||||||||
| Expr8720 | |||||||||
| Expr9545 | |||||||||
| Expr11262 | |||||||||
| Expr1029027 | |||||||||
| Expr1030523 | |||||||||
| Expr1149409 | |||||||||
| Expr2010595 | |||||||||
| Expr2028835 | |||||||||
| Drives_construct | WBCnstr00008886 | ||||||||
| WBCnstr00013478 | |||||||||
| WBCnstr00019897 | |||||||||
| WBCnstr00037251 | |||||||||
| Construct_product | WBCnstr00008886 | ||||||||
| WBCnstr00013480 | |||||||||
| WBCnstr00014110 | |||||||||
| WBCnstr00018525 | |||||||||
| WBCnstr00019897 | |||||||||
| WBCnstr00037251 | |||||||||
| Microarray_results (22) | |||||||||
| Expression_cluster (101) | |||||||||
| Interaction (24) | |||||||||
| WBProcess | WBbiopr:00000076 | ||||||||
| Map_info | Map | I | Position | 4.96984 | Error | 0.001736 | |||
| Positive | Positive_clone | F25D7 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 3948 | |||||||
| 3950 | |||||||||
| Reference (22) | |||||||||
| Method | Gene |
