abts-4 encodes an anion transporter; ABTS-4::GFP fusion proteins are expressed solely in the intestine, with highest levels seen in the most anterior and posterior gut cells and subcellular localization restricted to the basolateral membrane.
Predicted to enable transmembrane transporter activity. Predicted to be involved in bicarbonate transport; regulation of intracellular pH; and transmembrane transport. Located in basolateral plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including glucosephosphate dehydrogenase deficiency; hereditary elliptocytosis; and renal tubular acidosis. Is an ortholog of human SLC4A2 (solute carrier family 4 member 2) and SLC4A3 (solute carrier family 4 member 3).
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.