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WormBase Tree Display for Gene: WBGene00019427

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Name Class

WBGene00019427SMapS_parentSequenceK06A1
IdentityVersion2
NameCGC_nameatg-16.2Person_evidenceWBPerson649
Sequence_nameK06A1.5
Molecular_nameK06A1.5
K06A1.5.1
CE39948
Other_nameCELE_K06A1.5Accession_evidenceNDBBX284602
Public_nameatg-16.2
DB_infoDatabase (12)
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:31:01WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
229 Feb 2008 11:29:01WBPerson2970Name_changeCGC_nameatg-16.2
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classatg
Allele (30)
StrainWBStrain00033048
RNASeq_FPKM (74)
GO_annotation (18)
Contained_in_operonCEOP2729
Ortholog (36)
ParalogWBGene00017178Caenorhabditis elegansFrom_analysisInparanoid_8
Panther
WormBase-Compara
Structured_descriptionConcise_descriptionatg-16.2 encodes a divergent ortholog of the autophagic budding yeast protein Atg16p, and of human ATG16L1 (OMIM:610767, associated with Crohndisease) and ATG16L2; ATG-16.2 is paralogous to ATG-16.1; ATG-16.2 hasno obvious function in mass RNAi assays.Paper_evidenceWBPaper00031597
Curator_confirmedWBPerson567
Date_last_updated16 Mar 2008 00:00:00
Automated_descriptionInvolved in defense response to Gram-positive bacterium; gamete generation; and macroautophagy. Located in cytoplasm. Expressed in body wall musculature; embryonic cell; intestine; neurons; and pharyngeal muscle cell. Human ortholog(s) of this gene implicated in inflammatory bowel disease 10. Is an ortholog of human ATG16L1 (autophagy related 16 like 1) and ATG16L2 (autophagy related 16 like 2).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0110885Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:21498)
Molecular_infoCorresponding_CDSK06A1.5
Corresponding_CDS_historyK06A1.5:wp155
Corresponding_transcriptK06A1.5.1
Other_sequenceCJC03860_1
CR11609
CR01569
Oden_isotig18752
CRC02235_1
ES739747.1
CRC00622_1
HBC05383_1
CR05733
Associated_featureWBsf650147
WBsf665614
WBsf223177
WBsf223178
WBsf223179
Experimental_infoRNAi_resultWBRNAi00016651Inferred_automaticallyRNAi_primary
WBRNAi00092352Inferred_automaticallyRNAi_primary
WBRNAi00081157Inferred_automaticallyRNAi_primary
WBRNAi00102245Inferred_automaticallyRNAi_primary
WBRNAi00050018Inferred_automaticallyRNAi_primary
WBRNAi00092351Inferred_automaticallyRNAi_primary
WBRNAi00034001Inferred_automaticallyRNAi_primary
Expr_patternExpr11435
Expr1014835
Expr1038392
Expr1153711
Expr2009488
Expr2027725
Drives_constructWBCnstr00025846
Construct_productWBCnstr00019037
WBCnstr00025846
Microarray_results (20)
Expression_cluster (137)
Interaction (34)
Map_infoMapIIPosition-0.237977Error0.00254
PositivePositive_cloneK06A1Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
Reference (20)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene