ddl-1 encodes a coiled-coil protein orthologous to vertebrate CCD53; loss of ddl-1 activity via RNAi results in a daf-16-dependent increase in lifespan.
Involved in cytoplasmic sequestering of protein and determination of adult lifespan. Located in cytoplasm. Expressed in body wall musculature; neurons; pharynx; spermatheca; and vulval muscle. Is an ortholog of human WASHC3 (WASH complex subunit 3).
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.