WormBase Tree Display for Gene: WBGene00018473
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| WBGene00018473 | SMap | S_parent | Sequence | C08G9 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 3 | |||||||
| Name | CGC_name | cima-1 | Paper_evidence | WBPaper00043933 | |||||
| Person_evidence | WBPerson2264 | ||||||||
| Sequence_name | F45E4.11 | ||||||||
| Molecular_name | F45E4.11 | ||||||||
| F45E4.11.1 | |||||||||
| CE10512 | |||||||||
| Other_name | slc-17.10 | Person_evidence | WBPerson260 | ||||||
| CELE_F45E4.11 | Accession_evidence | NDB | BX284604 | ||||||
| Public_name | cima-1 | ||||||||
| DB_info | Database | AceView | gene | 4I419 | |||||
| WormQTL | gene | WBGene00018473 | |||||||
| NDB | locus_tag | CELE_F45E4.11 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00018473|UniProtKB=O44130 | |||||||
| family | PTHR11662 | ||||||||
| NCBI | gene | 24104589 | |||||||
| RefSeq | protein | NM_001307279.4 | |||||||
| TrEMBL | UniProtAcc | O44130 | |||||||
| UniProt_GCRP | UniProtAcc | O44130 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:31:00 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 26 Jul 2013 09:38:35 | WBPerson2970 | Name_change | CGC_name | cima-1 | ||||
| 3 | 27 Jun 2014 15:53:55 | WBPerson2970 | Name_change | Other_name | slc-17.10 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | cima | ||||||||
| Allele (34) | |||||||||
| Strain (14) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (11) | |||||||||
| Ortholog (30) | |||||||||
| Paralog (58) | |||||||||
| Structured_description | Concise_description | cima-1 encodes a membrane solute transporter that is a member of the SLC17 family of transporters; CIMA-1 functions postembryonially in epidermal cells to maintain synaptic contacts established during embryogenesis; specifically, CIMA-1 negatively regulates levels of the EGL-15(5A)/FGF receptor isoform to correctly position glia and control epidermal-glia cell adhesion; cima-1 expression begins during embryogenesis and continues through adulthood; in adults, CIMA-1 is mainly found in the epidermis, with some expression also seen in the intestine; a CIMA-1 reporter fusion localizes to lysosomes. | Paper_evidence | WBPaper00043941 | |||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 21 Oct 2013 00:00:00 | ||||||||
| Automated_description | Predicted to enable sialic acid transmembrane transporter activity. Involved in regulation of protein catabolic process and regulation of synapse organization. Located in lysosome. Expressed in hypodermis and intestine. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | F45E4.11 | |||||||
| Corresponding_transcript | F45E4.11.1 | ||||||||
| Other_sequence (39) | |||||||||
| Associated_feature | WBsf646104 | ||||||||
| WBsf660321 | |||||||||
| WBsf660322 | |||||||||
| WBsf997026 | |||||||||
| WBsf997027 | |||||||||
| WBsf997028 | |||||||||
| WBsf1017748 | |||||||||
| WBsf1017749 | |||||||||
| WBsf228560 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00022364 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00047403 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00112452 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00032303 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00047404 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr11186 | ||||||||
| Expr1017134 | |||||||||
| Expr1037961 | |||||||||
| Expr1151248 | |||||||||
| Expr2010016 | |||||||||
| Expr2028257 | |||||||||
| Drives_construct | WBCnstr00021826 | ||||||||
| WBCnstr00026491 | |||||||||
| Construct_product | WBCnstr00018206 | ||||||||
| WBCnstr00021824 | |||||||||
| WBCnstr00021825 | |||||||||
| WBCnstr00021826 | |||||||||
| WBCnstr00021827 | |||||||||
| WBCnstr00021828 | |||||||||
| WBCnstr00021829 | |||||||||
| WBCnstr00021830 | |||||||||
| WBCnstr00021840 | |||||||||
| WBCnstr00026491 | |||||||||
| Microarray_results (20) | |||||||||
| Expression_cluster (84) | |||||||||
| Interaction (27) | |||||||||
| Map_info | Map | IV | Position | 3.37504 | |||||
| Positive | Positive_clone | F45E4 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00043941 | ||||||||
| WBPaper00052604 | |||||||||
| WBPaper00059357 | |||||||||
| WBPaper00060850 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
