WormBase Tree Display for Gene: WBGene00017763
expand all nodes | collapse all nodes | view schema
| WBGene00017763 | SMap | S_parent | Sequence | F23H11 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | crls-1 | Person_evidence | WBPerson8897 | |||||
| Sequence_name | F23H11.9 | ||||||||
| Molecular_name | F23H11.9a | ||||||||
| F23H11.9a.1 | |||||||||
| CE09617 | |||||||||
| F23H11.9b | |||||||||
| CE37763 | |||||||||
| F23H11.9b.1 | |||||||||
| Other_name | CELE_F23H11.9 | Accession_evidence | NDB | BX284603 | |||||
| Public_name | crls-1 | ||||||||
| DB_info | Database (13) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:30:59 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 26 Feb 2009 11:04:20 | WBPerson9133 | Name_change | CGC_name | crls-1 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | crls | ||||||||
| Allele (45) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (23) | |||||||||
| Contained_in_operon | CEOP3048 | ||||||||
| Ortholog (35) | |||||||||
| Paralog | WBGene00019255 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | crls-1 encodes a cardiolipin synthase; by homology, CRLS-1 is predicted to catalyze cardiolipin biosynthesis from phosphatidylglycerol and cytidinediphosphate-diacylglycerol, and loss of crls-1 activity results in reduced levels of cardiolipin and elevated levels of phosphatidylglycerol; in C. elegans, crls-1 activity is required for normal germ cell mitochondrial membrane potential and cristae morphology, as well as for germ cell proliferation. | Paper_evidence | WBPaper00040537 | |||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 21 Dec 2011 00:00:00 | ||||||||
| Automated_description | Enables cardiolipin synthase activity. Involved in cardiolipin biosynthetic process; regulation of cell population proliferation; and regulation of mitochondrial membrane potential. Predicted to be located in mitochondrial inner membrane. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 57. Is an ortholog of human CRLS1 (cardiolipin synthase 1). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0070430 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:16148) | ||||
| Molecular_info | Corresponding_CDS | F23H11.9a | |||||||
| F23H11.9b | |||||||||
| Corresponding_CDS_history | F23H11.9:wp135 | ||||||||
| Corresponding_transcript | F23H11.9a.1 | ||||||||
| F23H11.9b.1 | |||||||||
| Other_sequence (35) | |||||||||
| Associated_feature | WBsf666549 | ||||||||
| WBsf666550 | |||||||||
| WBsf666551 | |||||||||
| WBsf991186 | |||||||||
| WBsf226155 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00013835 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00111229 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00023724 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00023212 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00045448 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00006523 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00023437 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00024011 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr1024443 | ||||||||
| Expr1037628 | |||||||||
| Expr1149367 | |||||||||
| Expr2010533 | |||||||||
| Expr2028773 | |||||||||
| Drives_construct | WBCnstr00027039 | ||||||||
| Construct_product | WBCnstr00027039 | ||||||||
| Microarray_results (22) | |||||||||
| Expression_cluster (54) | |||||||||
| Interaction (69) | |||||||||
| Map_info | Map | III | Position | -25.3228 | Error | 0.030952 | |||
| Positive | Positive_clone | F23H11 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00034409 | ||||||||
| WBPaper00036608 | |||||||||
| WBPaper00036609 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00039610 | |||||||||
| WBPaper00040537 | |||||||||
| WBPaper00042257 | |||||||||
| WBPaper00050263 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00056678 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
