Questions, Feedback & Help
Send us an email and we'll get back to you ASAP. Or you can read our Frequently Asked Questions.

WormBase Tree Display for Gene: WBGene00017054

expand all nodes | collapse all nodes | view schema

Name Class

WBGene00017054SMapS_parentSequenceD2024
IdentityVersion2
NameCGC_namegstk-2Person_evidenceWBPerson1763
Sequence_nameD2024.7
Molecular_nameD2024.7
D2024.7.1
CE04296
Other_nameCELE_D2024.7Accession_evidenceNDBBX284604
Public_namegstk-2
DB_infoDatabase (12)
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:30:58WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
227 Feb 2008 14:43:32WBPerson2970Name_changeCGC_namegstk-2
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classgstk
AlleleWBVar01453040
WBVar01453041
WBVar01499395
WBVar00428356
WBVar01499396
WBVar00428357
WBVar00428358
WBVar00428359
WBVar00428360
WBVar00428361
WBVar00264318
WBVar01786421
WBVar01499633
WBVar00920248
WBVar00920249
WBVar00920250
WBVar00920251
WBVar00920252
WBVar00920253
WBVar00920254
WBVar00920255
WBVar01687987
WBVar00920256
WBVar00920257
WBVar00920258
WBVar00920259
WBVar00920260
WBVar00920261
WBVar00920262
WBVar00920263
WBVar01500245
RNASeq_FPKM (74)
GO_annotation (15)
Ortholog (37)
ParalogWBGene00014251Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00020314Caenorhabditis elegansFrom_analysisPanther
Structured_descriptionConcise_descriptiongstk-2 encodes one of two C. elegans kappa class glutathione transferases; while gstk-2(RNAi) animals exhibit no obvious developmental or morphological abnormalities, animals doubly mutant for gstk-2 and gstk-1 exhibit decreased respiration and a lower concentration of the monounsaturated fatty acid cis-vaccenic acid; GSTK-2 is expressed primarily in the pharynx, muscles, and epidermis and localizes to mitochondria.Paper_evidenceWBPaper00035091
Curator_confirmedWBPerson1843
Date_last_updated14 Aug 2009 00:00:00
Automated_descriptionPredicted to enable glutathione peroxidase activity and glutathione transferase activity. Predicted to be involved in glutathione metabolic process. Located in mitochondrion. Expressed in body wall musculature; intestine; and pharynx. Is an ortholog of human GSTK1 (glutathione S-transferase kappa 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSD2024.7
Corresponding_transcriptD2024.7.1
Other_sequenceCBC12524_1
Associated_featureWBsf996915
WBsf996916
WBsf230235
WBsf230236
WBsf230237
Experimental_infoRNAi_result (11)
Expr_patternExpr8776
Expr1021154
Expr1037327
Expr1147459
Expr2012335
Expr2030572
Drives_constructWBCnstr00013514
WBCnstr00027605
Construct_productWBCnstr00013514
WBCnstr00027605
Microarray_results (21)
Expression_clusterWBPaper00031040:Cluster_5
WBPaper00031040:TGF-beta_adult_upregulated
WBPaper00032031:DConiospora_downregulated_cDNA_24h
WBPaper00037950:A-class-motor-neurons_L2-larva_expressed
WBPaper00037950:all-neurons_L1-larva_expressed
WBPaper00037950:AVA-neuron_L1-larva_expressed
WBPaper00037950:bodywall-muscle_L1-larva_expressed
WBPaper00037950:bodywall-muscle_L2-larva_expressed
WBPaper00037950:coelomocytes_embryo_enriched
WBPaper00037950:coelomocytes_L1-larva_expressed
WBPaper00037950:coelomocytes_L2-larva_expressed
WBPaper00037950:dopaminergic-neurons_L1-larva_expressed
WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
WBPaper00037950:dopaminergic-neurons_larva_enriched
WBPaper00037950:excretory-cell_L2-larva_expressed
WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed
WBPaper00037950:hypodermis_L1-larva_expressed
WBPaper00037950:hypodermis_L3-L4-larva_expressed
WBPaper00037950:intestine_L1-larva_expressed
WBPaper00037950:intestine_L2-larva_expressed
WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
WBPaper00038438:Harposporium_24hr_downregulated_RNAseq
WBPaper00040221:DAF-12_target_ALF4
WBPaper00042561:smgl-1(RNAi)_downregulated
WBPaper00044426:rotenone_24h_upregulated
WBPaper00044736:flat_dev_expression
WBPaper00045314:S.aureus-induced_N2
WBPaper00045390:tunicamycin_downregulated
WBPaper00045390:ubc-9(RNAi)_downregulated
WBPaper00045417:128Q-huntingtin_upreglated
WBPaper00045774:clk-1_downregulated
WBPaper00046497:B.thuringiensis_0.1mix_upregulated_6h
WBPaper00046497:B.thuringiensis_0.1mix_upregulated_12h
WBPaper00046497:B.thuringiensis_0.5mix_upregulated_6h
WBPaper00046497:B.thuringiensis_0.5mix_upregulated_12h
WBPaper00048923:Aging_regulated
WBPaper00049545:cco-1(RNAi)_downregulated
WBPaper00049545:jmjd-3.1(+)_downregulated
WBPaper00049942:hsf-1(RNAi)_downregulated
WBPaper00050468:hlh-30-dependent_Cry5B_regulated
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
WBPaper00050488:N2_vs_mir-34(OverExpression)_regulated_dauer_20C
WBPaper00050801:DAF-16_dauer_regulome
WBPaper00050990:GABAergic-neuron_expressed
WBPaper00050990:intestine_expressed
WBPaper00051558:aging_regulated
WBPaper00052884:emb-4(hc60)_upregulated
WBPaper00053184:sma-2(rax5)_upregulated
WBPaper00053184:sma-4(rax3)_upregulated
WBPaper00053302:stavudine_24h_regulated
WBPaper00053302:zidovudine_72h_regulated
WBPaper00053388:dauer_regulated_Cluster4
WBPaper00053599:female_vs_male_downregulated
WBPaper00053810:daf-2(e1370)_upregulated
WBPaper00053810:nuo-6(qm200)_upregulated
WBPaper00055354:eat-2(ad1116)_downregulated
WBPaper00055354:Psora-Allantoin_downregulated
WBPaper00055354:Rapamycin-Allantoin_downregulated
WBPaper00055354:Rapamycin-Rifampicin-Psora_upregulated
WBPaper00055354:Rapamycin-Rifampicin_upregulated
WBPaper00055648:sperm_expressed
WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
WBPaper00056090:E.faecalis_upregulated_N2
WBPaper00056139:soil-microbiota_downregulated
WBPaper00056161:male_enriched_siRNA
WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
WBPaper00056471:S.aureus-4h_downregulated_N2
WBPaper00056826:hmc_biased
WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
WBPaper00057041:unc-70(cas983)_downregulated
WBPaper00057143:ztf-11(RNAi)_upregulated
WBPaper00057288:iff-1(RNAi)_upregulated_transcript
WBPaper00058711:wdr-5(ok1417)_downregulated
WBPaper00058948:PA14_downregulated
WBPaper00059567:olrn-1(ums9)_regulated
WBPaper00059987:Wounding_upregulated
WBPaper00060100:SiNP_downregulated_mRNA
WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
WBPaper00060399:pqm-1(ok485)_upregulated_CoCl2_6hr
WBPaper00060526:plp-1(ok2155)_downregulated
WBPaper00060811:L1_vs_adult_upregulated_neural
WBPaper00061081:E.faecalis_upregulated_N2
WBPaper00061340:BWM_anterior
WBPaper00061527:acy-2-F35C5.11
WBPaper00061699:daf-18(ok480)_downregulated
WBPaper00061753:csr-1(tor159)_upregulated_25C
WBPaper00062159:hda-2(ok1479)_upregulated
WBPaper00062193:skn-1(RNAi)_upregulated
WBPaper00062325:muscle_enriched_coding-RNA
WBPaper00062345:bortezomib_4h_downregulated_N2
WBPaper00062590:Aging_downregulated_hypodermis
WBPaper00062590:Aging_downregulated_neuron
WBPaper00064005:starvation_upregulated_aptf-1(gk794)_mRNA
WBPaper00064005:starvation_upregulated_N2_mRNA
WBPaper00064071:NHR-49_interacting
WBPaper00064088:Day-1-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
WBPaper00064088:Day-1-adult_vs_L4_upregulated_fem-3(q20)
WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
WBPaper00064130:Beta-Amyloid_upregulated_protein
WBPaper00065096:Day10_vs_Day1_downregulated
WBPaper00065373:sek-1(km4)_downregulated_cisplatin
WBPaper00065373:sek-1(km4)_upregulated_Ref
cgc4489_group_17
WBPaper00026929:Resveratrol_regulated_daf-16
WBPaper00026929:sir-2.1_overexpression_regulated
WBPaper00030839:Embryo_Pan_Neuronal
WBPaper00030985:Enterococcus_faecalis_downregulated
WBPaper00031003:0hr_muscle_enriched
WBPaper00031003:24hr_muscle_enriched
WBPaper00031003:hlh_1_enriched
WBPaper00031003:total_muscle_enriched
WBPaper00032948:StarveUp1
WBPaper00035227:heat_shock_regulated
WBPaper00036286:Pattern_F
WBPaper00038172:tax-6null_up_regulated
WBPaper00040184:hcf-1up_sir-2.1up_daf-2up
WBPaper00040426:CYD-1_CDK-4_upregulated
WBPaper00040963:Q100_up
WBPaper00040963:Q200_up
WBPaper00041606:CE_S.marcescens_regulated
WBPaper00041939:control_vs_EtBr-exposed_48h
WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h
WBPaper00041939:UVC-EtBr-exposed_vs_EtBr-exposed_3h
WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
WBPaper00042234:xpa-1_upregulated
WBPaper00042274:tbx-2(bx59)_upregulated
WBPaper00044535:male_upregulated
WBPaper00045960:L4-lethargus_upregulated
WBPaper00047070:N2_starvation_upregulated
WBPaper00053236:Starvation_regulated_N2
InteractionWBInteraction000151486
WBInteraction000215297
WBInteraction000371371
WBInteraction000387413
WBInteraction000524867
WBInteraction000524868
Map_infoMapIVPosition3.31178Error0.000439
PositivePositive_cloneD2024Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00035091
WBPaper00038491
WBPaper00055090
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene