Questions, Feedback & Help
Send us an email and we'll get back to you ASAP. Or you can read our Frequently Asked Questions.

WormBase Tree Display for Gene: WBGene00016313

expand all nodes | collapse all nodes | view schema

Name Class

WBGene00016313SMapS_parentSequenceC32D5
IdentityVersion2
NameCGC_nameset-4Person_evidenceWBPerson1730
WBPerson268
WBPerson632
Sequence_nameC32D5.5
Molecular_nameC32D5.5
C32D5.5.1
CE01845
Other_nametag-337Person_evidenceWBPerson201
CELE_C32D5.5Accession_evidenceNDBBX284602
Public_nameset-4
DB_infoDatabase (13)
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:30:57WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
203 May 2007 10:33:07WBPerson2970Name_changeCGC_nameset-4
Other_nametag-337
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classset
Allele (24)
StrainWBStrain00027495
WBStrain00036235
WBStrain00050682
RNASeq_FPKM (74)
GO_annotation (16)
Ortholog (38)
Structured_descriptionConcise_descriptionset-4 encodes a putative histone H4 lysine-20 methyltransferase; SET-4 is orthologous to Drosophila SUV4-20, and to human SUV420H1 (OMIM:610881) and SUV420H2; set-4(RNAi) animals exhibit an extended adult fertile worm lifespan.Paper_evidenceWBPaper00005599
WBPaper00030864
WBPaper00031080
Curator_confirmedWBPerson567
Date_last_updated11 Oct 2007 00:00:00
Automated_descriptionPredicted to enable histone H4K20me methyltransferase activity. Involved in determination of adult lifespan. Predicted to be located in chromosome and nucleus. Expressed in several structures, including hypodermis and muscle cell. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 51. Is an ortholog of human KMT5B (lysine methyltransferase 5B) and KMT5C (lysine methyltransferase 5C).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0080232Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:24283)
Molecular_infoCorresponding_CDSC32D5.5
Corresponding_transcriptC32D5.5.1
Other_sequence (14)
Associated_featureWBsf650129
WBsf650130
WBsf665596
WBsf988134
WBsf1012362
WBsf223155
WBsf223156
Experimental_infoRNAi_resultWBRNAi00041670Inferred_automaticallyRNAi_primary
WBRNAi00011480Inferred_automaticallyRNAi_primary
WBRNAi00029415Inferred_automaticallyRNAi_primary
WBRNAi00091986Inferred_automaticallyRNAi_primary
WBRNAi00113446Inferred_automaticallyRNAi_primary
WBRNAi00091992Inferred_automaticallyRNAi_primary
WBRNAi00007949Inferred_automaticallyRNAi_primary
WBRNAi00091991Inferred_automaticallyRNAi_primary
WBRNAi00091514Inferred_automaticallyRNAi_primary
WBRNAi00091988Inferred_automaticallyRNAi_primary
Expr_patternExpr13301
Expr14355
Expr1010500
Expr1036978
Expr1145695
Expr2015780
Expr2034013
Drives_constructWBCnstr00028168
WBCnstr00039182
Construct_productWBCnstr00028168
Regulate_expr_clusterWBPaper00050801:SET-4_dauer_regulome
AntibodyWBAntibody00002748
Microarray_results (19)
Expression_cluster (112)
Interaction (35)
Map_infoMapIIPosition-0.381269Error0.000183
PositivePositive_cloneC32D5Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point5272
Pseudo_map_position
Reference (16)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene