WormBase Tree Display for Gene: WBGene00016034

WBGene00016034 SMap: S_parent: Sequence: C24A3
  Identity: Version: 1
    Name: Sequence_name: C24A3.4
      Molecular_name: C24A3.4
        C24A3.4.1
        CE40019
      Other_name: CELE_C24A3.4 Accession_evidence: NDB BX284606
      Public_name: C24A3.4
    DB_info: Database: AceView gene XJ613
        WormQTL gene WBGene00016034
        WormFlux gene WBGene00016034
        NDB locus_tag CELE_C24A3.4
        NCBI gene 181140
        RefSeq protein NM_077116.5
        TREEFAM TREEFAM_ID TF314188
        TrEMBL UniProtAcc Q18122
        UniProt_GCRP UniProtAcc Q18122
        OMIM gene 604489
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:30:56 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
    Status: Live
  Gene_info: Biotype: SO:0001217
    Allele (47)
    RNASeq_FPKM (74)
    GO_annotation: 00060250
      00060251
      00060252
      00060253
      00121721
    Contained_in_operon: CEOPX173
    Ortholog (34)
    Paralog: WBGene00014128 Caenorhabditis elegans From_analysis: TreeFam
            Inparanoid_8
            WormBase-Compara
    Structured_description: Automated_description: Predicted to enable alpha-methylacyl-CoA racemase activity. Predicted to be involved in bile acid metabolic process. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in several diseases, including alpha-methylacyl-CoA racemase deficiency; congenital bile acid synthesis defect 4; and urinary system cancer (multiple). Is an ortholog of human AMACR (alpha-methylacyl-CoA racemase). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:4450 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:451)
      DOID:11054 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:451)
      DOID:8634 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:451)
      DOID:0111068 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:451)
      DOID:0060602 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:451)
      DOID:3459 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:451)
  Molecular_info: Corresponding_CDS: C24A3.4
    Corresponding_CDS_history: C24A3.4:wp156
    Corresponding_transcript: C24A3.4.1
    Other_sequence: JI174337.1
      Oden_isotig20794
      PPC13413_1
      Dviv_isotig15323
      HQ662605.1
      MIC05051_1
      MI05754
      JI180010.1
    Associated_feature: WBsf663071
      WBsf663072
      WBsf1006295
      WBsf1006296
      WBsf1023493
      WBsf236104
      WBsf236105
  Experimental_info: RNAi_result: WBRNAi00011077 Inferred_automatically: RNAi_primary
      WBRNAi00041053 Inferred_automatically: RNAi_primary
      WBRNAi00029130 Inferred_automatically: RNAi_primary
      WBRNAi00092596 Inferred_automatically: RNAi_primary
      WBRNAi00011078 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1023350
      Expr1145091
      Expr2001032
      Expr2019250
    Drives_construct: WBCnstr00028373
    Construct_product: WBCnstr00028373
    Microarray_results (28)
    Expression_cluster: WBPaper00033065:cyc-1(RNAi)_upregulated
      WBPaper00033070:Rhine_downregulated
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
      WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00037950:intestine_embryo_enriched
      WBPaper00037950:intestine_embryo_SelectivelyEnriched
      WBPaper00037950:intestine_L2-larva_expressed
      WBPaper00042561:smgl-1(RNAi)_downregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00044786:emr-1(gk119)_downregulated
      WBPaper00045571:germline-ablation_upregulated
      WBPaper00046121:endoderm_unique
      WBPaper00046509:lin-35(n745)_downregulated
      WBPaper00048923:Aging_regulated
      WBPaper00048926:miaserin_upregulated_adult-day5
      WBPaper00049736:daf-2(e1370)_upregulated_15deg-then-25deg(12hr)
      WBPaper00049942:hsf-1(RNAi)_downregulated
      WBPaper00050080:rbr-2(tm3141)_upregulated
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050990:intestine_expressed
      WBPaper00053295:lin-22(ot267)_downregulated
      WBPaper00053295:lin-22(ot269)_downregulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053810:daf-2(e1370)_upregulated
      WBPaper00056161:hermaphrodite_enriched_siRNA
      WBPaper00056471:S.aureus-4h_upregulated_N2
      WBPaper00056826:hmc_biased
      WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
      WBPaper00057041:spc-1(cas971)_downregulated
      WBPaper00057041:unc-70(cas983)_downregulated
      WBPaper00057068:ints-4(RNAi)_downregulated
      WBPaper00058598:sin-3(tm1276)_downregulated
      WBPaper00058969:RIS_depleted
      WBPaper00059824:rnp-6(dh1127)_regulated_S.aureus
      WBPaper00059839:S.maltophilia_regulated
      WBPaper00060909:atfs-1(cmh15)_downregulated
      WBPaper00060911:prx-5(RNAi)_upregulated_mRNA
      WBPaper00060911:prx-5(RNAi)_upregulated_protein
      WBPaper00061203:let-418(n3536)_upregulated
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061203:spr-1(ok2144)_upregulated
      WBPaper00061340:CAN
      WBPaper00061479:mep-1(ne4629)_upregulated
      WBPaper00061527:C24A3.4_16071-ech-8
      WBPaper00061527:R10H10.3-T21H3.1
      WBPaper00061527:sre-33-ZK1025.1_8337
      WBPaper00061530:nhr-49(e2144)_downregulated
      WBPaper00061651:PVM_enriched
      WBPaper00061902:camt-1(ok515)_regulated_URX-AQR-PQR
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062606:rotenone_upregulated
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064632:daf-2(e1370)_upregulated_intestine
      WBPaper00064716:paraquat_downregulated
      WBPaper00064933:bcf-1(ylf1)_downregulated_transcript
      WBPaper00065158:AFD_depleted
      WBPaper00065835:Day11_vs_Day1_downregulated
      WBPaper00065841:20_0
      WBPaper00065841:20_2
      WBPaper00065841:39_2
      WBPaper00065841:54_0
      WBPaper00065841:73_0
      WBPaper00065841:145_0
      WBPaper00065984:pals-17(syb3980)_downregulated
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00066146:germline-inx-14(RNAi)_upregulated_PA14
      WBPaper00025032:cluster_63
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00031003:hlh_1_enriched
      WBPaper00034661:AgNPs_upregulated
      WBPaper00036286:Pattern_I
      WBPaper00037695:WC_5-day
      WBPaper00040210:Chlorpyrifos_16C_regulated
      WBPaper00040963:Q50_up
      WBPaper00041002:HF_3d_2.0mM_Up
      WBPaper00041174:environmental
      WBPaper00041174:genotype_environment_interaction
      WBPaper00041174:genotypic
      WBPaper00041174:genotypic_and_environmental
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00045263:0.1mM-paraquat_downregulated
      WBPaper00048989:N2_allantoin_upregulated
    Interaction: WBInteraction000178656
      WBInteraction000333545
  Map_info: Positive: Positive_clone: C24A3 Inferred_automatically: From sequence, transcript, pseudogene data
    Interpolated_map_position: X 0.488421
  Reference: WBPaper00038491
    WBPaper00042257
    WBPaper00055090
    WBPaper00062625
    WBPaper00064552
  Method: Gene