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WormBase Tree Display for Gene: WBGene00015971

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Name Class

WBGene00015971SMapS_parentSequenceC18E3
IdentityVersion2
NameCGC_nameswsn-2.2Person_evidenceWBPerson407
WBPerson552
Sequence_nameC18E3.2
Molecular_nameC18E3.2
C18E3.2.1
CE30249
Other_nameCELE_C18E3.2Accession_evidenceNDBBX284601
Public_nameswsn-2.2
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:30:56WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
211 Feb 2011 15:09:46WBPerson2970Name_changeCGC_nameswsn-2.2
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classswsn
Allele (31)
StrainWBStrain00029672
WBStrain00031318
WBStrain00037543
RNASeq_FPKM (74)
GO_annotation (16)
Contained_in_operonCEOP1946
Ortholog (44)
ParalogWBGene00044072Caenorhabditis elegansFrom_analysisInparanoid_8
Panther
WormBase-Compara
WBGene00044585Caenorhabditis elegansFrom_analysismodENCODE_Pseudogenes
WBGene00020779Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00010523Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionConcise_descriptionswsn-2.2 encodes a homolog of Swp73/BAF60, a component of the SWI/SNF complex that is conserved from yeast to mammals and that is involved in chromatin remodeling; swsn-2.2 is probably required during mitosis of the T cells for asymmetric cell division.Paper_evidenceWBPaper00004350
Curator_confirmedWBPerson1843
WBPerson567
Date_last_updated01 Aug 2011 00:00:00
Automated_descriptionPredicted to enable RNA polymerase II-specific DNA-binding transcription factor binding activity and transcription coregulator activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in condensed chromosome; nuclear envelope; and nucleoplasm. Expressed in several structures, including HSNL and HSNR. Used to study alcohol use disorder. Human ortholog(s) of this gene implicated in Coffin-Siris syndrome 11. Is an ortholog of human SMARCD1 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1); SMARCD2 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2); and SMARCD3 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoExperimental_modelDOID:1574Homo sapiensPaper_evidenceWBPaper00046494
Curator_confirmedWBPerson324
Date_last_updated20 May 2019 00:00:00
Potential_modelEFO:MONDO:0009506Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:11107)
DOID:0112372Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:11106)
Models_disease_assertedWBDOannot00000665
Molecular_infoCorresponding_CDSC18E3.2
Corresponding_transcriptC18E3.2.1
Other_sequence (12)
Associated_featureWBsf643191
WBsf643192
WBsf656176
WBsf983356
WBsf217501
Experimental_infoRNAi_resultWBRNAi00007940Inferred_automaticallyRNAi_primary
WBRNAi00040936Inferred_automaticallyRNAi_primary
WBRNAi00061241Inferred_automaticallyRNAi_primary
WBRNAi00093893Inferred_automaticallyRNAi_primary
WBRNAi00069103Inferred_automaticallyRNAi_primary
WBRNAi00016521Inferred_automaticallyRNAi_primary
WBRNAi00061240Inferred_automaticallyRNAi_primary
WBRNAi00093974Inferred_automaticallyRNAi_primary
WBRNAi00093943Inferred_automaticallyRNAi_primary
Expr_patternExpr16204
Expr16205
Expr1016633
Expr1036825
Expr1144983
Expr2017157
Expr2035293
Drives_constructWBCnstr00017369
WBCnstr00028413
WBCnstr00042800
Construct_productWBCnstr00028413
WBCnstr00042800
Regulate_expr_clusterWBPaper00049018:swsn-2.2(RNAi)_downregulated
WBPaper00049018:swsn-2.2(RNAi)_upregulated
WBPaper00049018:SWSN-2.2_interacting
AntibodyWBAntibody00002683
Microarray_results (24)
Expression_cluster (135)
Interaction (345)
Map_infoMapIPosition-1.58056Error0.006827
PositivePositive_cloneC18E3Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00031554
WBPaper00038491
WBPaper00043854
WBPaper00046494
WBPaper00049018
WBPaper00055090
WBPaper00060275
WBPaper00065308
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene