WormBase Tree Display for Gene: WBGene00015971

WBGene00015971 SMap: S_parent: Sequence: C18E3
  Identity: Version: 2
    Name: CGC_name: swsn-2.2 Person_evidence: WBPerson407
            WBPerson552
      Sequence_name: C18E3.2
      Molecular_name: C18E3.2
        C18E3.2.1
        CE30249
      Other_name: CELE_C18E3.2 Accession_evidence: NDB BX284601
      Public_name: swsn-2.2
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:30:56 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 11 Feb 2011 15:09:46 WBPerson2970 Name_change: CGC_name: swsn-2.2
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: swsn
    Allele (31)
    Strain: WBStrain00029672
      WBStrain00031318
      WBStrain00037543
    RNASeq_FPKM (74)
    GO_annotation (16)
    Contained_in_operon: CEOP1946
    Ortholog: WBGene00033166 Caenorhabditis briggsae From_analysis: OrthoMCL
            Inparanoid_8
            WormBase-Compara
      WBGene00062387 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00143177 Caenorhabditis brenneri From_analysis: Inparanoid_8
      WBGene00137870 Caenorhabditis japonica From_analysis: Inparanoid_8
            WormBase-Compara
      WBGene00115103 Pristionchus pacificus From_analysis: Inparanoid_8
            WormBase-Compara
      WBGene00192099 Caenorhabditis brenneri From_analysis: WormBase-Compara
      WBGene00227896 Brugia malayi From_analysis: WormBase-Compara
      CBOVI.g5325 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g5214 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g14791 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g1084 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g1967 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g22024 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g13408 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g15318 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g18914 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g16378 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cnig_chr_I.g1983 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold627.g6643 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_01000.g17441 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_21928 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_002271 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g13463 Oscheius tipulae From_analysis: WormBase-Compara
      Pan_g11879 Panagrellus redivivus From_analysis: WormBase-Compara
      Sp34_10348600 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrI_pilon.g667 Caenorhabditis elegans From_analysis: WormBase-Compara
      chrX_pilon.g20129 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00245094 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00263141 Strongyloides ratti From_analysis: WormBase-Compara
      SGD:S000000648 Saccharomyces cerevisiae From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            Panther
            PhylomeDB
      FB:FBgn0025463 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-030131-1835 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-080509-2 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-080215-1 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      ZFIN:ZDB-GENE-070912-491 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:11106 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:11107 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:11108 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:1914243 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:1933621 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:1933623 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      RGD:69289 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      RGD:1311869 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      RGD:1305406 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
    Paralog: WBGene00044072 Caenorhabditis elegans From_analysis: Inparanoid_8
            Panther
            WormBase-Compara
      WBGene00044585 Caenorhabditis elegans From_analysis: modENCODE_Pseudogenes
      WBGene00020779 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00010523 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Concise_description: swsn-2.2 encodes a homolog of Swp73/BAF60, a component of the SWI/SNF complex that is conserved from yeast to mammals and that is involved in chromatin remodeling; swsn-2.2 is probably required during mitosis of the T cells for asymmetric cell division. Paper_evidence: WBPaper00004350
          Curator_confirmed: WBPerson1843
            WBPerson567
          Date_last_updated: 01 Aug 2011 00:00:00
      Automated_description: Predicted to enable RNA polymerase II-specific DNA-binding transcription factor binding activity and transcription coregulator activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in condensed chromosome; nuclear envelope; and nucleoplasm. Expressed in several structures, including HSNL and HSNR. Used to study alcohol use disorder. Human ortholog(s) of this gene implicated in Coffin-Siris syndrome 11. Is an ortholog of human SMARCD1 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1); SMARCD2 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2); and SMARCD3 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Experimental_model: DOID:1574 Homo sapiens Paper_evidence: WBPaper00046494
          Curator_confirmed: WBPerson324
          Date_last_updated: 20 May 2019 00:00:00
    Potential_model: EFO:MONDO:0009506 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:11107)
      DOID:0112372 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:11106)
  Models_disease_asserted: WBDOannot00000665
  Molecular_info: Corresponding_CDS: C18E3.2
    Corresponding_transcript: C18E3.2.1
    Other_sequence (12)
    Associated_feature: WBsf643191
      WBsf643192
      WBsf656176
      WBsf983356
      WBsf217501
  Experimental_info: RNAi_result: WBRNAi00007940 Inferred_automatically: RNAi_primary
      WBRNAi00040936 Inferred_automatically: RNAi_primary
      WBRNAi00061241 Inferred_automatically: RNAi_primary
      WBRNAi00093893 Inferred_automatically: RNAi_primary
      WBRNAi00069103 Inferred_automatically: RNAi_primary
      WBRNAi00016521 Inferred_automatically: RNAi_primary
      WBRNAi00061240 Inferred_automatically: RNAi_primary
      WBRNAi00093974 Inferred_automatically: RNAi_primary
      WBRNAi00093943 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr16204
      Expr16205
      Expr1016633
      Expr1036825
      Expr1144983
      Expr2017157
      Expr2035293
    Drives_construct: WBCnstr00017369
      WBCnstr00028413
      WBCnstr00042800
    Construct_product: WBCnstr00028413
      WBCnstr00042800
    Regulate_expr_cluster: WBPaper00049018:swsn-2.2(RNAi)_downregulated
      WBPaper00049018:swsn-2.2(RNAi)_upregulated
      WBPaper00049018:SWSN-2.2_interacting
    Antibody: WBAntibody00002683
    Microarray_results (24)
    Expression_cluster (135)
    Interaction (345)
  Map_info: Map: I Position: -1.58056 Error: 0.006827
    Positive: Positive_clone: C18E3 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00031554
    WBPaper00038491
    WBPaper00043854
    WBPaper00046494
    WBPaper00049018
    WBPaper00055090
    WBPaper00060275
    WBPaper00065308
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene