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WormBase Tree Display for Gene: WBGene00015646

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Name Class

WBGene00015646SMapS_parentSequenceC09E8
IdentityVersion2
NameCGC_namemlt-10Person_evidenceWBPerson545
WBPerson3379
Sequence_nameC09E8.3
Molecular_nameC09E8.3
C09E8.3.1
CE19349
Other_nameC09E8.aCurator_confirmedWBPerson1983
RemarkOld cosmid naming mapped via unique overlapping PCR_product on CDSs
CELE_C09E8.3Accession_evidenceNDBBX284602
Public_namemlt-10
DB_infoDatabaseAceViewgene2A841
WormQTLgeneWBGene00015646
WormFluxgeneWBGene00015646
NDBlocus_tagCELE_C09E8.3
PanthergeneCAEEL|WormBase=WBGene00015646|UniProtKB=O76555
familyPTHR21523
NCBIgene173445
RefSeqproteinNM_061354.5
TREEFAMTREEFAM_IDTF315329
TrEMBLUniProtAccO76555
UniProt_GCRPUniProtAccO76555
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:30:56WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
228 Jul 2005 14:21:20WBPerson2970Name_changeCGC_namemlt-10
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classmlt
Allele (107)
StrainWBStrain00007913
WBStrain00007925
WBStrain00007926
WBStrain00007927
WBStrain00032646
RNASeq_FPKM (74)
GO_annotation00038482
00038483
00038484
00038485
Ortholog (39)
Paralog (13)
Structured_descriptionConcise_descriptionmlt-10 encodes a nematode-specific protein that contains a domain of unknown function, DUF644, and tandem proline- and hydroxy amino acid-rich repeats; mlt-10 is required for proper execution of the molting cycle, as well as a number of other processes including normal body shape, locomotion, and reproduction; MLT-10 is expressed transiently with each molting cycle in the hypodermis, except for the lateral seam cells, and in the pharyngeal myoepithelium; MLT-10 is secreted into the surrounding matrix and fluids during molting and also found in strands near the animal surface; mlt-10 expression in the hypodermis depends upon the nuclear hormone receptors NHR-23 and NHR-25; MLT-10 contains thirteen paralogs in the C. elegans genome that, along with MLT-10, are all members of a large family of conserved nematode proteins.Paper_evidenceWBPaper00036066
Curator_confirmedWBPerson1843
Date_last_updated26 Mar 2010 00:00:00
Automated_descriptionInvolved in cuticle development involved in collagen and cuticulin-based cuticle molting cycle and epidermis development. Located in extracellular space. Expressed in hypodermal cell and pharyngeal epithelial cell.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSC09E8.3
Corresponding_transcriptC09E8.3.1
Other_sequenceEX547584.1
ACC41112_1
SSC03996_1
CBC13394_1
JI468824.1
BXC01140_1
Associated_featureWBsf643913
WBsf717623
WBsf717624
WBsf986435
WBsf220766
WBsf220767
Experimental_infoRNAi_resultWBRNAi00010520Inferred_automaticallyRNAi_primary
WBRNAi00040201Inferred_automaticallyRNAi_primary
WBRNAi00028724Inferred_automaticallyRNAi_primary
WBRNAi00098168Inferred_automaticallyRNAi_primary
Expr_patternChronogram1648
Expr3696
Expr9014
Expr9015
Expr1022256
Expr1036700
Expr1144271
Expr2013604
Expr2031837
Drives_constructWBCnstr00000978
WBCnstr00006118
WBCnstr00006119
WBCnstr00006887
WBCnstr00011607
WBCnstr00013673
WBCnstr00028689
Construct_productWBCnstr00006116
WBCnstr00006117
WBCnstr00006118
WBCnstr00006119
WBCnstr00028689
Microarray_results (22)
Expression_cluster (256)
Interaction (36)
Map_infoMapIIPosition-15.5955Error0.000175
PositivePositive_cloneC09E8Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
Reference (13)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene