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WormBase Tree Display for Gene: WBGene00015646

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Name Class

WBGene00015646SMapS_parentSequenceC09E8
IdentityVersion2
NameCGC_namemlt-10Person_evidenceWBPerson545
WBPerson3379
Sequence_nameC09E8.3
Molecular_nameC09E8.3
C09E8.3.1
CE19349
Other_nameC09E8.aCurator_confirmedWBPerson1983
RemarkOld cosmid naming mapped via unique overlapping PCR_product on CDSs
CELE_C09E8.3Accession_evidenceNDBBX284602
Public_namemlt-10
DB_infoDatabaseAceViewgene2A841
WormQTLgeneWBGene00015646
WormFluxgeneWBGene00015646
NDBlocus_tagCELE_C09E8.3
PanthergeneCAEEL|WormBase=WBGene00015646|UniProtKB=O76555
familyPTHR21523
NCBIgene173445
RefSeqproteinNM_061354.5
TREEFAMTREEFAM_IDTF315329
TrEMBLUniProtAccO76555
UniProt_GCRPUniProtAccO76555
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:30:56WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
228 Jul 2005 14:21:20WBPerson2970Name_changeCGC_namemlt-10
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classmlt
Allele (107)
StrainWBStrain00007913
WBStrain00007925
WBStrain00007926
WBStrain00007927
WBStrain00032646
RNASeq_FPKM (74)
GO_annotation00038482
00038483
00038484
00038485
Ortholog (39)
Paralog (13)
Structured_descriptionConcise_descriptionmlt-10 encodes a nematode-specific protein that contains a domain of unknown function, DUF644, and tandem proline- and hydroxy amino acid-rich repeats; mlt-10 is required for proper execution of the molting cycle, as well as a number of other processes including normal body shape, locomotion, and reproduction; MLT-10 is expressed transiently with each molting cycle in the hypodermis, except for the lateral seam cells, and in the pharyngeal myoepithelium; MLT-10 is secreted into the surrounding matrix and fluids during molting and also found in strands near the animal surface; mlt-10 expression in the hypodermis depends upon the nuclear hormone receptors NHR-23 and NHR-25; MLT-10 contains thirteen paralogs in the C. elegans genome that, along with MLT-10, are all members of a large family of conserved nematode proteins.Paper_evidenceWBPaper00036066
Curator_confirmedWBPerson1843
Date_last_updated26 Mar 2010 00:00:00
Automated_descriptionInvolved in cuticle development involved in collagen and cuticulin-based cuticle molting cycle and epidermis development. Located in extracellular space. Expressed in hypodermal cell and pharyngeal epithelial cell.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSC09E8.3
Corresponding_transcriptC09E8.3.1
Other_sequenceEX547584.1
ACC41112_1
SSC03996_1
CBC13394_1
JI468824.1
BXC01140_1
Associated_featureWBsf643913
WBsf717623
WBsf717624
WBsf986435
WBsf220766
WBsf220767
Experimental_infoRNAi_resultWBRNAi00010520Inferred_automaticallyRNAi_primary
WBRNAi00040201Inferred_automaticallyRNAi_primary
WBRNAi00028724Inferred_automaticallyRNAi_primary
WBRNAi00098168Inferred_automaticallyRNAi_primary
Expr_patternChronogram1648
Expr3696
Expr9014
Expr9015
Expr1022256
Expr1036700
Expr1144271
Expr2013604
Expr2031837
Drives_constructWBCnstr00000978
WBCnstr00006118
WBCnstr00006119
WBCnstr00006887
WBCnstr00011607
WBCnstr00013673
WBCnstr00028689
Construct_productWBCnstr00006116
WBCnstr00006117
WBCnstr00006118
WBCnstr00006119
WBCnstr00028689
Microarray_results (22)
Expression_cluster (256)
Interaction (36)
Map_infoMapIIPosition-15.5955Error0.000175
PositivePositive_cloneC09E8Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00019538
WBPaper00028747
WBPaper00034317
WBPaper00034332
WBPaper00036066
WBPaper00039555
WBPaper00049531
WBPaper00052224
WBPaper00058870
WBPaper00060754
WBPaper00062715
WBPaper00065000
WBPaper00065116
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene