WormBase Tree Display for Gene: WBGene00014254
expand all nodes | collapse all nodes | view schema
WBGene00014254 | SMap | S_parent | Sequence | ZK1320 | ||
---|---|---|---|---|---|---|
Identity (6) | ||||||
Gene_info | Biotype | SO:0001217 | ||||
Gene_class | cyp | |||||
Allele (38) | ||||||
RNASeq_FPKM (74) | ||||||
GO_annotation | 00055359 | |||||
00055360 | ||||||
00055361 | ||||||
00055362 | ||||||
00055363 | ||||||
00055364 | ||||||
00120967 | ||||||
00120968 | ||||||
00120969 | ||||||
00120970 | ||||||
Ortholog (80) | ||||||
Paralog (12) | ||||||
Structured_description | Concise_description | cyp-13A10 encodes one of ~80 C. elegans cytochrome P450s: membrane-associated, heme-containing NADPH-dependent monooxygenases that catalyze the oxidative metabolism of a variety of exogenous and endogenous compounds. | Curator_confirmed | WBPerson1843 | ||
Date_last_updated | 20 Nov 2008 00:00:00 | |||||
Automated_description | Predicted to enable heme binding activity; iron ion binding activity; and oxidoreductase activity. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in several diseases, including Ghosal hematodiaphyseal syndrome; familial Mediterranean fever; and leukemia (multiple). Is an ortholog of several human genes including CYP3A4 (cytochrome P450 family 3 subfamily A member 4); CYP3A5 (cytochrome P450 family 3 subfamily A member 5); and CYP3A7 (cytochrome P450 family 3 subfamily A member 7). | Paper_evidence | WBPaper00065943 | |||
Curator_confirmed | WBPerson324 | |||||
WBPerson37462 | ||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | |||||
Date_last_updated | 29 Nov 2023 00:00:00 | |||||
Disease_info | Potential_model | DOID:8552 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2638) | |
DOID:3526 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:11609) | |||
DOID:2987 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2637) | |||
DOID:9952 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2638) | |||
DOID:0112251 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:11609) | |||
DOID:0080630 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2638) | |||
DOID:10825 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2638) | |||
DOID:1612 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2637) | |||
Molecular_info | Corresponding_CDS | ZK1320.4 | ||||
Corresponding_CDS_history | ZK1320.4:wp78 | |||||
ZK1320.4:wp134 | ||||||
Corresponding_transcript | ZK1320.4.1 | |||||
Other_sequence | Tcol_isotig15615 | |||||
CJC00249_1 | ||||||
PPC08967_1 | ||||||
Associated_feature | WBsf650448 | |||||
WBsf650449 | ||||||
WBsf223686 | ||||||
Experimental_info | RNAi_result | WBRNAi00092627 | Inferred_automatically | RNAi_primary | ||
WBRNAi00059235 | Inferred_automatically | RNAi_primary | ||||
Expr_pattern | Expr1012131 | |||||
Expr1036391 | ||||||
Expr1162665 | ||||||
Expr2010678 | ||||||
Expr2028918 | ||||||
Drives_construct | WBCnstr00029187 | |||||
Construct_product | WBCnstr00029187 | |||||
Microarray_results (17) | ||||||
Expression_cluster (181) | ||||||
Interaction (27) | ||||||
Map_info (3) | ||||||
Reference | WBPaper00037579 | |||||
WBPaper00038491 | ||||||
WBPaper00042257 | ||||||
WBPaper00055090 | ||||||
WBPaper00062515 | ||||||
WBPaper00064598 | ||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||
Method | Gene |