WormBase Tree Display for Gene: WBGene00014115

WBGene00014115 SMap: S_parent: Sequence: ZK858
  Identity: Version: 2
    Name (5)
    DB_info: Database (12)
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:55 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 21 Apr 2009 16:04:55 WBPerson9133 Name_change: CGC_name: gld-4
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: gld
    Allele (61)
    Strain: WBStrain00007425
    RNASeq_FPKM (74)
    GO_annotation (24)
    Ortholog: WBGene00059929 Caenorhabditis remanei From_analysis: TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00033394 Caenorhabditis briggsae From_analysis: Hillier-set
            OrthoMCL
            Inparanoid_8
            WormBase-Compara
      WBGene00155670 Caenorhabditis brenneri From_analysis: TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00161619 Caenorhabditis brenneri From_analysis: TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00122389 Caenorhabditis japonica From_analysis: TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00227831 Brugia malayi From_analysis: WormBase-Compara
      CBOVI.g9982 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g4159 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g17026 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g15463 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g2092 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g10424 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g17333 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g22142 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g16488 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP39.g16953 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g24176 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cni-gld-4 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold501.g2301 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_00260.g8151 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_05158 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_002450 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g09884 Oscheius tipulae From_analysis: WormBase-Compara
      Pan_g19658 Panagrellus redivivus From_analysis: WormBase-Compara
      Sp34_10114710 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrI_pilon.g1746 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00237790 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00260790 Strongyloides ratti From_analysis: WormBase-Compara
      WBGene00285351 Trichuris muris From_analysis: WormBase-Compara
      WBGene00297353 Trichuris muris From_analysis: WormBase-Compara
      SGD:S000005475 Saccharomyces cerevisiae From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      SGD:S000005243 Saccharomyces cerevisiae From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      FB:FBgn0030049 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Hieranoid
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      FB:FBgn0039251 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            OrthoFinder
            OrthoInspector
            Panther
      ZFIN:ZDB-GENE-041021-1 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      ZFIN:ZDB-GENE-041021-2 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      HGNC:16705 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      HGNC:30758 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      MGI:2682295 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      MGI:1917820 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      RGD:1307356 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      RGD:1309587 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
    Structured_description: Concise_description: gld-4 encodes a noncanonical poly(A) polymerase orthologous to Saccharomyces cerevisiae Trf4/5p; GLD-4 activity is required for early meiotic progression of male and female gametes in the absence of GLD-2 and for regulation of gld-1 mRNA levels; GLD-4 physically interacts with GLS-1 which stimulates GLD-4 poly(A) polymerase activity in vivo; GLD-4 is expressed predominantly in germ cells and localizes to the cytoplasm and to P granules. Paper_evidence: WBPaper00033036
          Curator_confirmed: WBPerson1843
          Date_last_updated: 26 Sep 2011 00:00:00
      Automated_description: Enables poly(A) RNA polymerase activity. Involved in mRNA polyadenylation. Located in P granule. Part of polysome. Expressed in Z2; Z3; and germ line. Is an ortholog of human TENT4A (terminal nucleotidyltransferase 4A) and TENT4B (terminal nucleotidyltransferase 4B). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: ZK858.1
    Corresponding_CDS_history: ZK858.1:wp101
      ZK858.1:wp193
    Corresponding_transcript: ZK858.1.1
    Other_sequence: ES412194.1
      Dviv_isotig16462
      JI178419.1
      HBC19083_1
    Associated_feature (22)
  Experimental_info: RNAi_result (11)
    Expr_pattern: Expr8623
      Expr11998
      Expr1022314
      Expr1036324
      Expr1163210
      Expr2012089
      Expr2030325
    Regulate_expr_cluster: WBPaper00045729:gld-4(RNAi)_downregulated
      WBPaper00045729:gld-4(RNAi)_upregulated
    Antibody: WBAntibody00001897
      WBAntibody00001898
      WBAntibody00001899
      WBAntibody00001900
    Microarray_results (25)
    Expression_cluster (139)
    Interaction (115)
  Map_info: Map: I Position: 3.59898 Error: 0.008849
    Positive: Positive_clone: ZK858 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (16)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene