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WormBase Tree Display for Gene: WBGene00014115

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Name Class

WBGene00014115SMapS_parentSequenceZK858
IdentityVersion2
NameCGC_namegld-4Paper_evidenceWBPaper00033036
Person_evidenceWBPerson555
Sequence_nameZK858.1
Molecular_nameZK858.1
ZK858.1.1
CE42850
Other_nameCELE_ZK858.1Accession_evidenceNDBBX284601
Public_namegld-4
DB_infoDatabase (12)
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:55WBPerson1971EventImportedInitial conversion from CDS class of WS125
221 Apr 2009 16:04:55WBPerson9133Name_changeCGC_namegld-4
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classgld
Allele (61)
StrainWBStrain00007425
RNASeq_FPKM (74)
GO_annotation (24)
Ortholog (42)
Structured_descriptionConcise_descriptiongld-4 encodes a noncanonical poly(A) polymerase orthologous to Saccharomyces cerevisiae Trf4/5p; GLD-4 activity is required for early meiotic progression of male and female gametes in the absence of GLD-2 and for regulation of gld-1 mRNA levels; GLD-4 physically interacts with GLS-1 which stimulates GLD-4 poly(A) polymerase activity in vivo; GLD-4 is expressed predominantly in germ cells and localizes to the cytoplasm and to P granules.Paper_evidenceWBPaper00033036
Curator_confirmedWBPerson1843
Date_last_updated26 Sep 2011 00:00:00
Automated_descriptionEnables poly(A) RNA polymerase activity. Involved in mRNA polyadenylation. Located in P granule. Part of polysome. Expressed in Z2; Z3; and germ line. Is an ortholog of human TENT4A (terminal nucleotidyltransferase 4A) and TENT4B (terminal nucleotidyltransferase 4B).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSZK858.1
Corresponding_CDS_historyZK858.1:wp101
ZK858.1:wp193
Corresponding_transcriptZK858.1.1
Other_sequenceES412194.1
Dviv_isotig16462
JI178419.1
HBC19083_1
Associated_feature (22)
Experimental_infoRNAi_result (11)
Expr_patternExpr8623
Expr11998
Expr1022314
Expr1036324
Expr1163210
Expr2012089
Expr2030325
Regulate_expr_clusterWBPaper00045729:gld-4(RNAi)_downregulated
WBPaper00045729:gld-4(RNAi)_upregulated
AntibodyWBAntibody00001897
WBAntibody00001898
WBAntibody00001899
WBAntibody00001900
Microarray_results (25)
Expression_cluster (139)
Interaction (115)
Map_infoMapIPosition3.59898Error0.008849
PositivePositive_cloneZK858Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
Reference (16)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene