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WormBase Tree Display for Gene: WBGene00013458

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Name Class

WBGene00013458SMapS_parentSequenceY67A10A
IdentityVersion2
NameCGC_nameclc-8Person_evidenceWBPerson260
Sequence_nameY67A10A.9
Molecular_nameY67A10A.9
Y67A10A.9.1
CE24570
Other_nameCELE_Y67A10A.9Accession_evidenceNDBBX284604
Public_nameclc-8
DB_infoDatabaseAceViewgene4P163
WormQTLgeneWBGene00013458
WormFluxgeneWBGene00013458
NDBlocus_tagCELE_Y67A10A.9
PanthergeneCAEEL|WormBase=WBGene00013458|UniProtKB=Q9U1V0
familyPTHR35574
NCBIgene178380
RefSeqproteinNM_070345.6
TREEFAMTREEFAM_IDTF316179
TrEMBLUniProtAccQ9U1V0
UniProt_GCRPUniProtAccQ9U1V0
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:55WBPerson1971EventImportedInitial conversion from CDS class of WS125
219 Apr 2021 01:27:01WBPerson1983Name_changeCGC_nameclc-8
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classclc
Allele (87)
RNASeq_FPKM (74)
GO_annotation00098420
00120303
Ortholog (28)
ParalogWBGene00000523Caenorhabditis elegansFrom_analysisTreeFam
WBGene00000526Caenorhabditis elegansFrom_analysisTreeFam
WBGene00011014Caenorhabditis elegansFrom_analysisPanther
WBGene00016067Caenorhabditis elegansFrom_analysisPanther
Structured_descriptionConcise_descriptionY67A10A.9 encodes a claudin homolog that may be required for normal cohesion of apical junctions in epithelia; Y67A10A.9 is worm-specific, with obvious homologs only in C. elegans; Y67A10A.9 has no obvious function in mass RNAi assays; claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water.Paper_evidenceWBPaper00004651
WBPaper00004961
WBPaper00005946
WBPaper00005975
WBPaper00012856
WBPaper00018356
Curator_confirmedWBPerson567
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to be located in membrane.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSY67A10A.9
Corresponding_transcriptY67A10A.9.1
Other_sequenceMI07373
MI07150
MI07157
MIC06423_1
Dviv_isotig27108
CJC03908_1
MIC06829_1
JI166547.1
Associated_featureWBsf717204
WBsf718236
WBsf718237
WBsf998567
WBsf998568
WBsf998569
WBsf1018649
WBsf1018650
WBsf229499
WBsf229500
Experimental_infoRNAi_resultWBRNAi00037722Inferred_automaticallyRNAi_primary
WBRNAi00106947Inferred_automaticallyRNAi_primary
WBRNAi00057974Inferred_automaticallyRNAi_primary
WBRNAi00000436Inferred_automaticallyRNAi_primary
Expr_patternExpr1020530
Expr1036017
Expr1161402
Expr2008197
Expr2026438
Drives_constructWBCnstr00029632
Construct_productWBCnstr00029632
Microarray_results (18)
Expression_clusterWBPaper00031040:TGF-beta_adult_upregulated
WBPaper00033065:cyc-1(RNAi)_upregulated
WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
WBPaper00037950:dopaminergic-neurons_L1-larva_expressed
WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
WBPaper00037950:excretory-cell_L2-larva_expressed
WBPaper00037950:hypodermis_L1-larva_expressed
WBPaper00037950:hypodermis_L3-L4-larva_expressed
WBPaper00037950:hypodermis_larva_enriched
WBPaper00037950:hypodermis_larva_SelectivelyEnriched
WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
WBPaper00038168:lin-15B(n744)_downregulated
WBPaper00038438:D.coniospora_12hr_downregulated_RNAseq
WBPaper00038438:E.faecalis_24hr_upregulated_TilingArray
WBPaper00038438:P.lumniescens_24hr_upregulated_TilingArray
WBPaper00041071:spe-44_downregulated
WBPaper00044426:rotenone_24h_downregulated
WBPaper00044736:flat_dev_expression
WBPaper00046121:ecdoderm_unique
WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
WBPaper00047131:daf-2(e1370)_upregulated_hel-1(gk148684)-background
WBPaper00048988:neuron_expressed
WBPaper00049018:ham-3(RNAi)_upregulated
WBPaper00049545:jmjd-3.1(+)_upregulated
WBPaper00049545:rgef-1p-jmjd-1.2(+)_upregulated
WBPaper00049635:dop-1(vs100)_upregulated
WBPaper00050163:chd-3(eh4);let-418(RNAi)_upregulated_24-cell-embryo
WBPaper00050163:chd-3(eh4);let-418(RNAi)_upregulated_100-cell-embryo
WBPaper00050193:cec-4(ok3124)_downregulated_L1
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
WBPaper00051404:alg-1(gk214)_upregulated
WBPaper00051404:alg-2(ok304)_upregulated
WBPaper00053184:sma-4(rax3)_upregulated
WBPaper00053295:lin-22(icb38)_upregulated
WBPaper00053295:lin-22(ot269)_upregulated
WBPaper00053302:alovudine_24h_regulated
WBPaper00053302:stavudine_24h_regulated
WBPaper00053302:stavudine_72h_regulated
WBPaper00053302:zidovudine_72h_regulated
WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_L1_SMARTseq
WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_starved-L1_Truseq
WBPaper00053321:PGCs_depleted_NuGen
WBPaper00053388:dauer_regulated_Cluster1
WBPaper00053771:up_at_dpy-7(e88)
WBPaper00054758:alg-1(gk204)_upregulated
WBPaper00055334:DLC-1_interacting
WBPaper00055626:pry-1(mu38)_upregulated
WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
WBPaper00056139:soil-microbiota_upregulated
WBPaper00056169:rrf-3(pk1426)_upregulated_embryo
WBPaper00056284:ints-11(RNAi)_downregulated
WBPaper00056330:glycine_downregulated
WBPaper00056443:sek-1(km4)_upregulated
WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
WBPaper00056471:S.aureus-4h_downregulated_N2
WBPaper00056826:SGP_biased
WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
WBPaper00057068:numr-1(RNAi)_downregulated_Cadmium
WBPaper00057140:pptr-1(tm3103)_downregulated
WBPaper00058598:mex-1(or286)_upregulated
WBPaper00058598:mex-3(eu149)_upregulated
WBPaper00058598:sin-3(tm1276)_downregulated
WBPaper00058598:spn-4(tm291)_upregulated
WBPaper00058691:cfp-1(tm6369)_upregulated
WBPaper00058691:set-2(bn129)_upregulated
WBPaper00058711:wdr-5(ok1417)_upregulated
WBPaper00059328:mrps-5(RNAi)_upregulated_mRNA
WBPaper00059421:daf-1(m40);daf-3(mgDf90)_downregulated
WBPaper00059421:daf-3(mgDf90)_downregulated
WBPaper00059605:mut-16(pk710)_upregulated
WBPaper00059664:srbc-48(ac23)_upregulated
WBPaper00060014:set-2(zr2012)_upregulated
WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
WBPaper00060909:atfs-1(cmh15)_downregulated
WBPaper00061203:sin-3(tm1276)_upregulated
WBPaper00061203:spr-1(ok2144)_upregulated
WBPaper00061340:ADEsh
WBPaper00061340:AMso
WBPaper00061340:CEPsh
WBPaper00061340:CEPso
WBPaper00061340:Excretory_duct_and_pore
WBPaper00061340:Excretory_gland
WBPaper00061340:G2_and_W_blasts
WBPaper00061340:Glia
WBPaper00061340:hyp1V_and_ant_arc_V
WBPaper00061340:hyp3
WBPaper00061340:ILsh_OLLsh_OLQsh
WBPaper00061340:ILso
WBPaper00061340:Parents_of_PHsh_hyp8_hyp9
WBPaper00061341:28C_24h_upregulated
WBPaper00061479:hda-1(ne4752)_upregulated
WBPaper00061479:mep-1(ne4629)_upregulated
WBPaper00061527:nhr-107_19485-nhr-109_3743
WBPaper00061527:R07G3.8_9125-ric-4_17408
WBPaper00062159:hda-2(ok1479)_upregulated
WBPaper00062184:PA14_downregulated
WBPaper00062193:skn-1(RNAi)_downregulated
WBPaper00062325:muscle_depleted_coding-RNA
WBPaper00064005:starvation_downregulated_aptf-1(gk794)_mRNA
WBPaper00064005:starvation_downregulated_N2_mRNA
WBPaper00064088:Day-1-adult_vs_L4_downregulated_fem-3(q20)
WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
WBPaper00064088:Day-3-adult_vs_L4_downregulated_fem-3(q20)
WBPaper00064156:lbp-3(overexpress)_upregulated
WBPaper00064306:Agaro-oligosaccharides_upregulated
WBPaper00064721:fasn-1(g14)_downregulated_starved
WBPaper00064769:him-17(me24)_upregulated
WBPaper00065096:25C_vs_20C_downregulated
WBPaper00065096:Day10_vs_Day1_downregulated
WBPaper00065749:endu-2(tm4977)_upregulated
WBPaper00065749:Heat-Shock_downregulated_endu-2(tm4977)
WBPaper00065749:Heat-Shock_downregulated_N2
WBPaper00065835:Day5_vs_Day1_downregulated
WBPaper00065841:45_0
WBPaper00065841:123_0
WBPaper00065926:pgph-2(overepxreesion)_upregulated_glucose
WBPaper00065975:P-body_vs_oocyte_enriched
WBPaper00065993:glp-1(e2141)_upregulated
WBPaper00066062:xrep-4(lax137)_upregulated
WBPaper00066110:tetraploid_vs_diploid_upregulated
WBPaper00066146:germline-inx-14(RNAi)_upregulated_PA14
WBPaper00025141:N2_Expressed_Genes
WBPaper00031003:0hr_muscle_depleted
WBPaper00031003:24hr_muscle_depleted
WBPaper00031003:total_muscle_depleted
WBPaper00031532:Larva_Pan_Neuronal_Depleted
WBPaper00032165:differentially_expressed_with_age_medoid_2
WBPaper00035084:embryo_enriched_AIN-2_IP
WBPaper00035084:L1_enriched_AIN-2_IP
WBPaper00035084:L2_enriched_AIN-2_IP
WBPaper00035084:L3_enriched_AIN-2_IP
WBPaper00035084:L4_enriched_AIN-2_IP
WBPaper00036130:mir-243_up_regulated
WBPaper00036286:Pattern_C
WBPaper00038172:crh-1null_up_regulated
WBPaper00038172:tax-6null_up_regulated
WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2
WBPaper00041174:environmental
WBPaper00041174:genotypic
WBPaper00041174:genotypic_and_environmental
WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
WBPaper00041939:UVC-EtBr-exposed_vs_EtBr-exposed_51h
WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h
WBPaper00041960:N2_fasting_upregulated_anytime
WBPaper00045015:nhr-25(RNAi)_downregulated
WBPaper00045673:colistin_upregulated
WBPaper00046853:AOBr_M.aeruginosa-batch-culture_downregulated
WBPaper00053236:Starvation_regulated_GR1307
WBPaper00053236:Starvation_regulated_N2
InteractionWBInteraction000544621
WBInteraction000559865
Map_infoPositivePositive_cloneY67A10AInferred_automaticallyFrom sequence, transcript, pseudogene data
Interpolated_map_positionIV11.8576
MethodGene