WormBase Tree Display for Gene: WBGene00013308

WBGene00013308 SMap: S_parent: Sequence: Y57G11C
  Identity: Version: 4
    Name: CGC_name: nuo-3 Person_evidence: WBPerson1157
      Sequence_name: Y57G11C.12
      Molecular_name: Y57G11C.12
        Y57G11C.12.1
        CE14948
        Y57G11C.12.2
      Other_name: ndua-6 Person_evidence: WBPerson555
        CELE_Y57G11C.12 Accession_evidence: NDB BX284604
      Public_name: nuo-3
    DB_info: Database: WormQTL gene WBGene00013308
        WormFlux gene WBGene00013308
        NDB locus_tag CELE_Y57G11C.12
        Panther gene CAEEL|WormBase=WBGene00013308|UniProtKB=O18236
          family PTHR12964
        NCBI gene 36805062
        RefSeq protein NM_001392444.1
        TrEMBL UniProtAcc O18236
        UniProt_GCRP UniProtAcc O18236
        OMIM gene 602138
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:54 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 31 Aug 2005 14:07:05 WBPerson2970 Name_change: CGC_name: nuo-3
        3 06 Mar 2018 14:43:22 WBPerson4025 Event: Split_into: WBGene00303007
        4 16 Jan 2023 18:37:21 WBPerson51134 Name_change: Other_name: ndua-6
      Split_into: WBGene00303007
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: nuo
    Allele (27)
    Strain: WBStrain00003089
      WBStrain00055406
    RNASeq_FPKM (74)
    GO_annotation: 00031815
      00031816
      00031817
      00031818
      00031819
      00031820
      00031821
      00031822
      00031823
    Contained_in_operon: CEOP5614
    Ortholog: WBGene00071676 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00040260 Caenorhabditis briggsae From_analysis: OrthoMCL
            OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00162641 Caenorhabditis brenneri From_analysis: OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00127743 Caenorhabditis japonica From_analysis: Inparanoid_8
            WormBase-Compara
      CBOVI.g8585 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g2970 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g9468 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g7535 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g3450 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g15839 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g652 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP40.g22215 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_00836.g14489 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cang_2012_03_13_08085.g21279 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cni-nuo-3 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold630.g21261 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_00908.g16653 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_15903 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_012869 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g02772 Oscheius tipulae From_analysis: WormBase-Compara
      Sp34_40182400 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrIV_pilon.g12537 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00264711 Strongyloides ratti From_analysis: WormBase-Compara
      FB:FBgn0033570 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
      ZFIN:ZDB-GENE-040426-1124 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      HGNC:7690 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:1914380 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      RGD:1309818 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
    Structured_description: Concise_description: The nuo-3 locus encodes two distinct, non-overlapping proteins: Y57G11C.12a (homologous to human C3orf10/BRICK1, a component of the WAVE1 complex) and Y57G11C.12b (a putativeNADH-ubiquinone oxidoreductase alpha subunit, homologous to human NDUFA6 [OMIM:602138]). Person_evidence: WBPerson242
          Curator_confirmed: WBPerson567
          Date_last_updated: 12 May 2008 00:00:00
      Automated_description: Predicted to be involved in response to oxidative stress. Predicted to be located in mitochondrial inner membrane and respirasome. Predicted to be part of mitochondrial respiratory chain complex I. Human ortholog(s) of this gene implicated in Alzheimer's disease and nuclear type mitochondrial complex I deficiency 33. Is an ortholog of human NDUFA6 (NADH:ubiquinone oxidoreductase subunit A6). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0112097 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:7690)
      DOID:10652 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:7690)
  Molecular_info: Corresponding_CDS: Y57G11C.12
    Corresponding_CDS_history: Y57G11C.12a:wp264
      Y57G11C.12b:wp264
    Corresponding_transcript: Y57G11C.12.1
      Y57G11C.12.2
    Corresponding_transcript_history: Y57G11C.12c:wp264
    Associated_feature: WBsf652383
      WBsf981851
      WBsf998642
      WBsf231227
  Experimental_info: RNAi_result (35)
    Expr_pattern: Chronogram977
      Expr7077
      Expr1012642
      Expr1035936
      Expr1161096
      Expr2014529
      Expr2032768
    Drives_construct: WBCnstr00003574
      WBCnstr00029696
    Construct_product: WBCnstr00029696
    Microarray_results (32)
    Expression_cluster (107)
    Interaction (87)
  Map_info: Map: IV Position: 12.5086 Error: 0.002306
    Positive: Positive_clone: Y57G11C Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00005928
    WBPaper00026715
    WBPaper00031194
    WBPaper00033840
    WBPaper00037471
    WBPaper00038491
    WBPaper00041233
    WBPaper00048636
    WBPaper00055090
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene