tag-273 encodes a LIM-type zinc finger domain-containing protein with similarity to human LIM domain and actin-binding protein 1 (HGNC:LIMA1); RNAi experiments indicate that TAG-273 is required for normal reproduction; about 3% to 10% of tag-273 transcripts are RNA edited to change A to G resulting in a change to residue 688 from an N to a S.
Predicted to enable actin filament binding activity. Predicted to be involved in actin filament bundle assembly. Predicted to be located in actin cytoskeleton and plasma membrane. Is an ortholog of human LIMA1 (LIM domain and actin binding 1).
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.