WormBase Tree Display for Gene: WBGene00013241
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| WBGene00013241 | SMap | S_parent | Sequence | Y56A3A | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | ung-1 | Person_evidence | WBPerson3500 | |||||
| Sequence_name | Y56A3A.29 | ||||||||
| Molecular_name (12) | |||||||||
| Other_name | CELE_Y56A3A.29 | Accession_evidence | NDB | BX284603 | |||||
| Public_name | ung-1 | ||||||||
| DB_info | Database (13) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:54 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 25 Jul 2005 11:07:18 | WBPerson2970 | Name_change | CGC_name | ung-1 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | ung | ||||||||
| Allele (82) | |||||||||
| Strain | WBStrain00033256 | ||||||||
| WBStrain00051048 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (25) | |||||||||
| Contained_in_operon | CEOP3746 | ||||||||
| Ortholog (37) | |||||||||
| Structured_description | Concise_description | ung-1 encodes a uracil-DNA glycosylase; UNG-1 is required for genomic stability in somatic cells, and possibly also in germline, as well as for the recruitment of ATL-1 and RAD-51 to chromatin after depletion of dUTPase by dut-1(RNAi); ung-1(qa7600) or ung-1(RNAi) partially suppresses the lethality of dut-1(RNAi); purified UNG-1 can remove uracil from both U:G and U:A base pairs in DNA, and with lesser efficiency from single-stranded substrates. | Paper_evidence | WBPaper00005736 | |||||
| WBPaper00028477 | |||||||||
| WBPaper00031934 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 28 Oct 2011 00:00:00 | ||||||||
| Automated_description | Enables uracil DNA N-glycosylase activity. Involved in base-excision repair. Located in nucleus. Human ortholog(s) of this gene implicated in dysgammaglobulinemia and immunodeficiency with hyper IgM type 5. Is an ortholog of human UNG (uracil DNA glycosylase). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:11702 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:12572) | ||||
| DOID:0060759 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:12572) | ||||||
| Molecular_info | Corresponding_CDS | Y56A3A.29a | |||||||
| Y56A3A.29b | |||||||||
| Y56A3A.29c | |||||||||
| Y56A3A.29d | |||||||||
| Corresponding_transcript | Y56A3A.29a.1 | ||||||||
| Y56A3A.29b.1 | |||||||||
| Y56A3A.29c.1 | |||||||||
| Y56A3A.29d.1 | |||||||||
| Other_sequence (26) | |||||||||
| Associated_feature | WBsf666440 | ||||||||
| WBsf994545 | |||||||||
| WBsf994546 | |||||||||
| WBsf1016122 | |||||||||
| WBsf1016123 | |||||||||
| WBsf227620 | |||||||||
| WBsf227621 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00021077 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00097782 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00057596 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00037546 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00097702 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00097704 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00097781 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00062464 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00064079 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr1027598 | ||||||||
| Expr1035899 | |||||||||
| Expr1161013 | |||||||||
| Expr2017926 | |||||||||
| Expr2036062 | |||||||||
| Regulate_expr_cluster | WBPaper00036291:ung-1_regulated | ||||||||
| WBPaper00064257:UNG-1_interacting | |||||||||
| Microarray_results (31) | |||||||||
| Expression_cluster (144) | |||||||||
| Interaction (38) | |||||||||
| Map_info | Map | III | Position | 13.672 | Error | 0.053292 | |||
| Positive | Positive_clone | Y56A3A | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference (21) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
