WormBase Tree Display for Gene: WBGene00013241
expand all nodes | collapse all nodes | view schema
WBGene00013241 | SMap | S_parent | Sequence | Y56A3A | |||
---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||
Name | CGC_name | ung-1 | Person_evidence | WBPerson3500 | |||
Sequence_name | Y56A3A.29 | ||||||
Molecular_name (12) | |||||||
Other_name | CELE_Y56A3A.29 | Accession_evidence | NDB | BX284603 | |||
Public_name | ung-1 | ||||||
DB_info | Database (13) | ||||||
Species | Caenorhabditis elegans | ||||||
History | Version_change (2) | ||||||
Status | Live | ||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | ung | ||||||
Allele (82) | |||||||
Strain | WBStrain00033256 | ||||||
WBStrain00051048 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (25) | |||||||
Contained_in_operon | CEOP3746 | ||||||
Ortholog (37) | |||||||
Structured_description | Concise_description | ung-1 encodes a uracil-DNA glycosylase; UNG-1 is required for genomic stability in somatic cells, and possibly also in germline, as well as for the recruitment of ATL-1 and RAD-51 to chromatin after depletion of dUTPase by dut-1(RNAi); ung-1(qa7600) or ung-1(RNAi) partially suppresses the lethality of dut-1(RNAi); purified UNG-1 can remove uracil from both U:G and U:A base pairs in DNA, and with lesser efficiency from single-stranded substrates. | Paper_evidence | WBPaper00005736 | |||
WBPaper00028477 | |||||||
WBPaper00031934 | |||||||
Curator_confirmed | WBPerson1843 | ||||||
WBPerson567 | |||||||
Date_last_updated | 28 Oct 2011 00:00:00 | ||||||
Automated_description | Enables uracil DNA N-glycosylase activity. Involved in base-excision repair. Located in nucleus. Human ortholog(s) of this gene implicated in dysgammaglobulinemia and immunodeficiency with hyper IgM type 5. Is an ortholog of human UNG (uracil DNA glycosylase). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Disease_info | Potential_model | DOID:11702 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:12572) | ||
DOID:0060759 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:12572) | ||||
Molecular_info | Corresponding_CDS | Y56A3A.29a | |||||
Y56A3A.29b | |||||||
Y56A3A.29c | |||||||
Y56A3A.29d | |||||||
Corresponding_transcript | Y56A3A.29a.1 | ||||||
Y56A3A.29b.1 | |||||||
Y56A3A.29c.1 | |||||||
Y56A3A.29d.1 | |||||||
Other_sequence (26) | |||||||
Associated_feature | WBsf666440 | ||||||
WBsf994545 | |||||||
WBsf994546 | |||||||
WBsf1016122 | |||||||
WBsf1016123 | |||||||
WBsf227620 | |||||||
WBsf227621 | |||||||
Experimental_info | RNAi_result | WBRNAi00021077 | Inferred_automatically | RNAi_primary | |||
WBRNAi00097782 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00057596 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00037546 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00097702 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00097704 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00097781 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00062464 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00064079 | Inferred_automatically | RNAi_primary | |||||
Expr_pattern | Expr1027598 | ||||||
Expr1035899 | |||||||
Expr1161013 | |||||||
Expr2017926 | |||||||
Expr2036062 | |||||||
Regulate_expr_cluster | WBPaper00036291:ung-1_regulated | ||||||
WBPaper00064257:UNG-1_interacting | |||||||
Microarray_results (31) | |||||||
Expression_cluster (144) | |||||||
Interaction (38) | |||||||
Map_info | Map | III | Position | 13.672 | Error | 0.053292 | |
Positive | Positive_clone | Y56A3A | Inferred_automatically | From sequence, transcript, pseudogene data | |||
Pseudo_map_position | |||||||
Reference (21) | |||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
Method | Gene |