WormBase Tree Display for Gene: WBGene00013025
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| WBGene00013025 | SMap | S_parent | Sequence | Y49A3A | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 3 | |||||||
| Name | CGC_name | vha-13 | |||||||
| Sequence_name | Y49A3A.2 | ||||||||
| Molecular_name | Y49A3A.2 | ||||||||
| Y49A3A.2.1 | |||||||||
| CE22210 | |||||||||
| Other_name | phi-51 | Person_evidence | WBPerson2582 | ||||||
| Y49A3A.b | Curator_confirmed | WBPerson1983 | |||||||
| Remark | Old cosmid naming mapped via unique overlapping PCR_product on CDSs | ||||||||
| CELE_Y49A3A.2 | Accession_evidence | NDB | BX284605 | ||||||
| Public_name | vha-13 | ||||||||
| DB_info | Database (13) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:54 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 05 Jul 2004 15:50:25 | WBPerson1971 | Name_change | CGC_name | vha-13 | ||||
| 3 | 17 Mar 2005 13:54:35 | WBPerson2970 | Name_change | Other_name | phi-51 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | vha | ||||||||
| Allele (34) | |||||||||
| Strain | WBStrain00002259 | ||||||||
| WBStrain00002389 | |||||||||
| WBStrain00051361 | |||||||||
| WBStrain00051764 | |||||||||
| WBStrain00051767 | |||||||||
| WBStrain00054681 | |||||||||
| WBStrain00055526 | |||||||||
| WBStrain00054688 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (17) | |||||||||
| Contained_in_operon | CEOP5412 | ||||||||
| Ortholog (42) | |||||||||
| Paralog | WBGene00000229 | Caenorhabditis elegans | From_analysis | WormBase-Compara | |||||
| WBGene00004959 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00006921 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00010419 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00012040 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| Structured_description | Concise_description | vha-13 encodes an ortholog of subunit A of the cytoplasmic (V1) domainof vacuolar proton-translocating ATPase (V-ATPase); VHA-13 is predictedto hydrolyse ATP as part of a cytosolic VHA-12/VHA-13 heterohexamer,whose activity drives the V-ATPase rotor; VHA-13 levels are lowered inmutants with either abnormally low or abnormally high calcineurinlevels, and elevated in mutants lacking both calcineurin andcalreticulin; VHA-13 is dispensable for alae formation, like the V1subunit VHA-8, but not like the V0 subunits VHA-1 and VHA-4. | Paper_evidence | WBPaper00006525 | |||||
| WBPaper00026649 | |||||||||
| WBPaper00027022 | |||||||||
| WBPaper00027024 | |||||||||
| WBPaper00027697 | |||||||||
| WBPaper00028773 | |||||||||
| WBPaper00028774 | |||||||||
| WBPaper00028775 | |||||||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 19 Nov 2006 00:00:00 | ||||||||
| Automated_description | Predicted to enable proton-transporting ATPase activity, rotational mechanism. Involved in lysosomal lumen acidification. Predicted to be part of proton-transporting V-type ATPase, V1 domain. Expressed in head. Human ortholog(s) of this gene implicated in autosomal recessive cutis laxa type IID and developmental and epileptic encephalopathy 93. Is an ortholog of human ATP6V1A (ATPase H+ transporting V1 subunit A). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0070129 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:851) | ||||
| DOID:0112275 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:851) | ||||||
| Molecular_info | Corresponding_CDS | Y49A3A.2 | |||||||
| Corresponding_transcript | Y49A3A.2.1 | ||||||||
| Other_sequence (145) | |||||||||
| Associated_feature (23) | |||||||||
| Experimental_info | RNAi_result (18) | ||||||||
| Expr_pattern | Chronogram1537 | ||||||||
| Expr7016 | |||||||||
| Expr7017 | |||||||||
| Expr1022390 | |||||||||
| Expr1035790 | |||||||||
| Expr1160437 | |||||||||
| Expr2017979 | |||||||||
| Expr2036115 | |||||||||
| Drives_construct | WBCnstr00002973 | ||||||||
| WBCnstr00004482 | |||||||||
| Microarray_results (29) | |||||||||
| Expression_cluster (212) | |||||||||
| Interaction (134) | |||||||||
| Map_info | Map | V | Position | 6.24843 | Error | 0.0041 | |||
| Positive | Positive_clone | Y49A3A | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference (18) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
