WormBase Tree Display for Gene: WBGene00012553
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WBGene00012553 | SMap | S_parent | Sequence | Y37D8A | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 3 | |||||||
Name | CGC_name | cox-5A | Person_evidence | WBPerson117 | |||||
WBPerson7169 | |||||||||
Sequence_name | Y37D8A.14 | ||||||||
Molecular_name | Y37D8A.14 | ||||||||
Y37D8A.14.1 | |||||||||
CE20218 | |||||||||
Other_name | cco-2 | Person_evidence | WBPerson1157 | ||||||
CELE_Y37D8A.14 | Accession_evidence | NDB | BX284603 | ||||||
Public_name | cox-5A | ||||||||
DB_info | Database (11) | ||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 26 May 2004 16:54:53 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
2 | 31 Aug 2005 14:07:05 | WBPerson2970 | Name_change | CGC_name | cco-2 | ||||
3 | 05 Sep 2017 13:25:30 | WBPerson2970 | Name_change | CGC_name | cox-5A | ||||
Other_name | cco-2 | ||||||||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | cox | ||||||||
Allele (24) | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (12) | |||||||||
Ortholog (38) | |||||||||
Structured_description | Concise_description | cco-2 encodes the C. elegans ortholog of the cytochrome c oxidase (COX) subunit Va (COX Va); loss of cco-2 activity via RNAi results in a shortened life span, reduced fertility, and defects in mitochondrial respiratory chain function. | Paper_evidence | WBPaper00032427 | |||||
Curator_confirmed | WBPerson1843 | ||||||||
Date_last_updated | 08 Nov 2010 00:00:00 | ||||||||
Automated_description | Predicted to enable metal ion binding activity. Involved in mitochondrial electron transport, cytochrome c to oxygen. Predicted to be located in mitochondrial inner membrane. Predicted to be part of mitochondrial respiratory chain complex IV. Human ortholog(s) of this gene implicated in cytochrome-c oxidase deficiency disease. Is an ortholog of human COX5A (cytochrome c oxidase subunit 5A). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Disease_info | Potential_model | DOID:0070505 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2267) | ||||
Molecular_info | Corresponding_CDS | Y37D8A.14 | |||||||
Corresponding_transcript | Y37D8A.14.1 | ||||||||
Other_sequence (143) | |||||||||
Associated_feature (15) | |||||||||
Experimental_info | RNAi_result (17) | ||||||||
Expr_pattern | Expr1017887 | ||||||||
Expr1035556 | |||||||||
Expr1159398 | |||||||||
Expr2009765 | |||||||||
Expr2028005 | |||||||||
Microarray_results (26) | |||||||||
Expression_cluster (116) | |||||||||
Interaction (95) | |||||||||
Map_info | Map | III | Position | 19.5686 | Error | 0.139069 | |||
Positive | Positive_clone | Y37D8A | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Pseudo_map_position | |||||||||
Reference | WBPaper00026715 | ||||||||
WBPaper00030741 | |||||||||
WBPaper00031194 | |||||||||
WBPaper00032427 | |||||||||
WBPaper00038491 | |||||||||
WBPaper00049828 | |||||||||
WBPaper00055090 | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |