WormBase Tree Display for Gene: WBGene00012448

WBGene00012448 SMap: S_parent: Sequence: CHROMOSOME_V
  Identity: Version: 2
    Name: CGC_name: cyp-33D3
      Sequence_name: Y17D7A.4
      Molecular_name: Y17D7A.4
        Y17D7A.4.1
        CE16589
      Other_name: CELE_Y17D7A.4 Accession_evidence: NDB BX284605
      Public_name: cyp-33D3
    DB_info: Database: AceView gene 5T310
        WormQTL gene WBGene00012448
        WormFlux gene WBGene00012448
        NDB locus_tag CELE_Y17D7A.4
        Panther gene CAEEL|WormBase=WBGene00012448|UniProtKB=G5EE22
          family PTHR24300
        NCBI gene 189444
        RefSeq protein NM_075278.4
        TrEMBL UniProtAcc G5EE22
        UniProt_GCRP UniProtAcc G5EE22
        OMIM gene 601130
            608713
            610670
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:53 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 21 Sep 2004 09:38:16 WBPerson1971 Name_change: CGC_name: cyp-33D3
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: cyp
    Allele (116)
    RNASeq_FPKM (74)
    GO_annotation (15)
    Ortholog (114)
    Paralog (44)
    Structured_description: Automated_description: Predicted to enable heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Predicted to be involved in organic acid metabolic process and xenobiotic metabolic process. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in several diseases, including Keshan disease; glucose metabolism disease (multiple); and hematologic cancer (multiple). Is an ortholog of several human genes including CYP2B6 (cytochrome P450 family 2 subfamily B member 6); CYP2C19 (cytochrome P450 family 2 subfamily C member 19); and CYP2C8 (cytochrome P450 family 2 subfamily C member 8). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model (46)
  Molecular_info: Corresponding_CDS: Y17D7A.4
    Corresponding_CDS_history: Y17D7A.4:wp106
    Corresponding_transcript: Y17D7A.4.1
    Other_sequence (20)
    Associated_feature: WBsf982076
      WBsf1003019
      WBsf1021557
  Experimental_info: RNAi_result: WBRNAi00036657 Inferred_automatically: RNAi_primary
      WBRNAi00092667 Inferred_automatically: RNAi_primary
      WBRNAi00055560 Inferred_automatically: RNAi_primary
      WBRNAi00095077 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1021931
      Expr1159061
      Expr2010722
      Expr2028960
    Microarray_results (15)
    Expression_cluster (106)
    Interaction (35)
  Map_info: Map: V Position: 18.0657 Error: 0.02692
    Positive: Positive_clone: Y17D7A Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00038491
    WBPaper00055090
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene